Amelanotic melanoma and pyogenic granuloma. Peculiarities of the differential diagnosis

封面

如何引用文章

全文:

开放存取 开放存取
受限制的访问 ##reader.subscriptionAccessGranted##
受限制的访问 订阅存取

详细

INTRODUCTION: Nodular melanoma is a rapidly progressive skin tumour with a high risk of methastasis even on early stages. This fact leads to necessity of non-invasive procedures, which can verify this diagnosis before surgery. Nodular forms of amelanotic melanoma can be hardly diagnosed because of their unusual diagnostic and dermatoscopic features.

CASE REPORT: Pyogenic granuloma is the most difficult disease for differential diagnosis. It is a benign vascular formation, which mimics nodular amelanotic melanoma.

作者简介

Azizzhon Zikiryachodzhaev

P.A. Hertsen Moscow Oncology Research Center, Moscow, Russian Federation

Email: ivertieva@gmail.com
ORCID iD: 0000-0001-7141-2502
俄罗斯联邦, Moscow

E. Saribekyan

P.A. Hertsen Moscow Oncology Research Center, Moscow, Russian Federation

Email: ivertieva@gmail.com
ORCID iD: 0000-0002-1559-1304
俄罗斯联邦, Moscow

E. Vertieva

I.M. Sechenov First Moscow State Medical University (Sechenov University)

编辑信件的主要联系方式.
Email: ivertieva@gmail.com
ORCID iD: 0000-0002-1088-2911

MD, PhD

俄罗斯联邦, Moscow

I. Pestin

P.A. Hertsen Moscow Oncology Research Center, Moscow, Russian Federation

Email: ivertieva@gmail.com
俄罗斯联邦, Moscow

参考

  1. Guggenheim M, Hug U, Jung F, Rousson V, Aust M, Calcagni M, et al. Morbidity and recurrence after completion lymph node dissection following sentinel lymph node biopsy in cutaneous malignant melanoma. Ann Surg. 2008;247(4):687-93. doi: 10.1097/SLA.0b013e318161312a
  2. Mack L, McKinnon J. Controversies in the management of metastatic melanoma to regional lymphatic basins. J Surg Oncol. 2004;86(4):189-99. doi: 10.1002/jso.20080
  3. Yoradjian A, Azevedo M, Cattini L, Basso R. Pyogenic granuloma: Description of two unusual cases and review of the literature. Surg Cosmetic Dermatol. 2013;5(3):263-8.
  4. Lin R, Janniger C. Pyogenic granuloma. Cutis. 2004;74(4):229-33.
  5. Zaballos P, Carulla M, Ozdemir F, Zalaudek I, Bañuls J, Llambrich A, et al. Dermoscopy of pyogenic granuloma: a morphological study. Br J Dermatol. 2010;163(6):1229-37. doi: 10.1111/j.1365-2133.2010.10040.x
  6. Lacarrubba F, Caltabiano R, Micali G. Dermoscopic and histological correlation of an atypical case of pyogenic granuloma. Pediatr Dermatol. 2013;30(4):499-501. doi: 10.1111/pde.12123
  7. Papageorgiou C, Ioannides D, Apalla Z. Dermoscopy of difficult-to-diagnose Melanomas. Serbian J Dermatol Venereol. 2016;8(3):121-7.
  8. Togawa Y. Dermoscopy for the diagnosis of melanoma: an overview. Austin J Dermatol. 2017;4(3):1080.

补充文件

附件文件
动作
1. JATS XML
下载
2. Fig. 1. Patient M., 58 years old. Pyogenic granuloma. a - macroscopic picture; a node of bright red color, soft consistency, there is a hemorrhagic discharge on the surface; b - dermatoscopic picture: red homogeneous zones, weakly expressed white bridges, blue homogeneous pigmentation along the periphery.

下载 (275KB)
索引源数据
3. Fig. 2. Histological specimen. A tumor with an ulcerated skin surface (blue arrow), multilobular vascular structures (green arrow). Staining with hematoxylin and eosin. x 100.

下载 (561KB)
索引源数据
4. Fig. 3. Histological specimen. The tumor is represented by full-blooded capillaries (blue arrow). There is a pronounced mixed cell inflammation in the stroma (green arrow). Staining with hematoxylin and eosin. x 200.

下载 (504KB)
索引源数据
5. Fig. 4. 4. Patient L., 32 years old. Pyogenic granuloma during pregnancy, 34 weeks. a - pink knot with hemorrhagic crust on the surface; b - dermatoscopic picture: milky-red globular zones, white bridges, ulceration zone.

下载 (227KB)
索引源数据
6. Fig. 5. Histological specimen. Tumor with adjacent tissues. Hyperplasia of the epithelium over the tumor. Expanded full-blooded tumor capillaries. Staining with hematoxylin and eosin. x 50.

下载 (525KB)
索引源数据
7. Fig. 6. Patient Sh., 78 years old. Nodular non-pigmented melanoma of the skin of the left cheek. a - a knot of dense consistency with an erosive surface; b - dermatoscopy of non-pigmented melanoma: polymorphic atypical vessels.

下载 (308KB)
索引源数据

版权所有 © Eco-Vector, 2020


 


##common.cookie##