电邮这篇文章 Translation cellular immunotherapy of idiopathic and immunosuppressive Kaposi's sarcoma
- 作者: Kartashova M.1, Kildyushevsky A.1, Molochkov A.1, Fedulkina V.1
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隶属关系:
- M.F. Vladimirsky Moscow Regional Research and Clinical Institute
- 期: 卷 16, 编号 3 (2013)
- 页面: 13-18
- 栏目: Articles
- URL: https://journals.rcsi.science/1560-9588/article/view/36758
- DOI: https://doi.org/10.17816/dv36758
- ID: 36758
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全文:
详细
Translation cellular immunotherapy with ammifurine photosensitizer and UV irradiation (spectrum A) of cellular mononuclear suspension (λ = 320-340 nm, 90 min), followed by its reinfusion, were carried out in 20 patients with Kaposi’s sarcoma (15 with the idiotypical and 5 with immunosuppressive type) aged 32-75 years. Evaluation of the immune status of patients, including phenotyping, was carried out before and after therapy and demonstrated the treatment efficiency, shown by the time course of the clinical picture and periods of disease remission. The treatment efficiency is explained by induction of antitumor immunological surveillance. Relevant publications (8 references) are discussed.
作者简介
M. Kartashova
M.F. Vladimirsky Moscow Regional Research and Clinical Institute
Email: maxa.ka@mail.ru
кандидат мед. наук, научный сотрудник
A. Kildyushevsky
M.F. Vladimirsky Moscow Regional Research and Clinical Instituteдоктор мед. наук, профессор, ведущий научный сотрудник
A. Molochkov
M.F. Vladimirsky Moscow Regional Research and Clinical Instituteдоктор мед. наук, профессор
V. Fedulkina
M.F. Vladimirsky Moscow Regional Research and Clinical Institute
参考
- Молочков А.В., Казанцева И.А., Гурцевич В. Э. Саркома Капоши. М.: БИНОМ; 2000.
- Moore P.S., Gao S.J., Dominguez G., Cesarman E., Lungu O., Knowles D.M., et al. Primary characterization of a herpesvirus agent associated with Kaposi’s sarcoma. J. Virol. 1996; 70(1): 549-58.
- Renne R., Zhong W., Herndier B., McGrath M., Abbey N., Kedes D.,, Ganem D. Lytic growth of Kaposi’s sarcoma-associated herpesvirus (human herpesvirus 8) in culture. Nat. Med. 1996; 2(3): 342-6.
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- Кильдюшевский А.В., Молочков В А., Ольшанский А.Я., Молочков А.В., Фомин А.М., Гордиевская М.С. и др. Способ лечения Т-клеточных лимфом и саркомы Капоши. Патент № 2401671 от 20.10.2010. Изобретения и полезные модели. 2010; 29.
- Timmerman J.M., Levy R. Dendritic cell vaccines for cancer immunotherapy. Annu. Rev. Med. 1999; 50: 507-29.
- Aichele P., Brduscha-Riem K., Zinkernagel R.M., Hengartner H., Pircher H. T cell priming versus T cell tolerance induced by synthetic peptides. J. Exp. Med. 1995; 182(1): 261-6.
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