VITILIGO AND COMORBID PSYCHOSOMATIC DISORDERS


Cite item

Full Text

Abstract

Vitiligo is a chronic idiopathic disease characterized by appearance of depigmented spots and discolored hairs in various parts of the body due to the destruction and reducing the number of melanocytes. Despite the absence of somatogenic appearance psychosomatic aspects of vitiligo are extremely relevant to study in view of high psychosocial significance associated with the pronounced stigmatizing effects. 62 vitiligo patients were examined. Among comorbid psychosomatic disorders there were found out psychogenic manifestations - 25 (40.3%) and nosogenic reactions due to stress effect of the dermatosis - 37 (50.7%): sociophobic - 17, masked hypochondria - 13, overvalued hypochondria of beauty - 7 patients. Psychogenic manifestations with the participation of objectively severe and subjectively significant factors can attribute vitiligo to psychosomatic skin diseases. In the clinical picture of nosogenic disorders, various forms of dissociation between the prevalence of dermatosis and subjective reaction to the cosmetic defect were revealed, which is due to the structure of the personality and somatoperceptive accentuation of the patient. The results can be implemented in dermatological practice, which will significantly optimize the treatment and compliance of patients with vitiligo. Objective: a complex clinical (dermatological, psychopathological) and psychological study of psychosomatic disorders in vitiligo.

About the authors

Asmik A. Varzhapetyan

Department of skin and venereal diseases of I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: asmik_var@mail.ru
postgraduate of the Department of skin and venereal diseases of I.M. Sechenov First Moscow State Medical University (Sechenov University), 119435, Moscow, Russian Federation Moscow, 119435, Russian Federation

I. Yu Dorozhenok

Department of Psychiatry and Psychosomatics, Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University (Sechenov University); Mental Health Research Center

Moscow, 119991, Russian Federation; Moscow, 115522, Russian Federation

K. M Lomonosov

Department of skin and venereal diseases of I.M. Sechenov First Moscow State Medical University (Sechenov University)

Moscow, 119435, Russian Federation

References

  1. Picardo M., Dell’Anna M.L., Ezzedine K., Hamzavi I., Harris J.E., Parsad D., Taieb A. Vitiligo. Nat. Rev. Dis. Primers. 2015; (1): 15011. doi: 10.1038/nrdp.2015.11.
  2. Teasdale E., Muller I., Abdullah Sani A., Thomas K.S., Stuart B., Santer M. Views and experiences of seeking information and help for vitiligo: a qualitative study of written accounts. BMJ Open. 2018; 8(1): e018652.
  3. Mahajan V.K., Vashist S., Chauhan P.S., Mehta K.I.S., Sharma V., Sharma A. Clinico-epidemiological profile of patients with vitiligo: a retrospective study from a tertiary care center of North India. Indian Dermatol Online J. 2019; 10(1): 38-44.
  4. Catucci Boza J., Giongo N., Machado P., Horn R, Fabbrin A., Cestari T. Quality of life impairment in children and adults with vitiligo: a cross-sectional study based on dermatology-specific and disease-specific quality of life instruments. Dermatology. 2016; 232(5): 619-25.
  5. Ezzedine K., Lim H.W., Suzuki T., Katayama I., Hamzavi I., Lan C.C., et al.; Vitiligo Global Issue Consensus Conference Panelists. Revised classification/nomenclature of vitiligo and related issues: the vitiligo global issues consensus conference. Pigment Cell Melanoma Res. 2012; 25(3): E1-13.
  6. Altalhab S., AlJasser M.I., Mulekar S.V., Al Issa A., Mulekar S., Diaz J., Diallo A., Ezzedine K. Six-year follow-up of vitiligo patients successfully treated with autologous non-cultured melanocyte-keratinocyte transplantation. J. Eur. Acad. Dermatol. Venereol. 2019; 33(6): 1172-6.
  7. Wang Y., Li S., Li C. Perspectives of new advances in the pathogenesis of vitiligo: from oxidative stress to autoimmunity. Med. Sci. Monit. 2019; 25:1017-23.
  8. Silverberg J.I., Silverberg N.B. Vitiligo disease triggers: psychological stressors preceding the onset of disease. Cutis. 2015; 95(5): 255-62.
  9. Кошевенко Ю.Н. Клиника, этиология, патогенез, лечение, реабилитация, профилактика. М.: Косметика и медицина; 2002.
  10. Khurrum H., AlGhamdi K.M. Prepubertal and postpubertal vitiligo: a multivariate comparative study in 375 patients. An Bras Dermatol. 2017; 92(6): 811-5.
  11. Sarkar S., Sarkar T., Sarkar A., Das S. Vitiligo and psychiatric morbidity: a profile from a vitiligo clinic of a rural-based tertiary care center of eastern India. Indian J. Dermatol. 2018; 63(4): 281-4.
  12. Sawant N.S., Vanjari N.A., Khopkar U. Gender differences in depression, coping, stigma, and quality of life in patients of vitiligo. Dermatol. Res. Practice. 2019; 2019: 6879412.
  13. Kota R.S., Vora R.V., Varma J.R., Kota S.K., Patel T.M., Ganjiwale J. Study on assessment of quality of life and depression in patients of vitiligo. Indian Dermatol. Online J. 2019; 10(2): 153-7.
  14. Patel K.R., Singam V., Rastogi S., Lee H.H., Silverberg N.B., Silverberg J.I. Association of vitiligo with hospitalization for mental health disorders in US adults. J. Eur. Acad. Dermatol. Venereol. 2019; 33(1): 191-7.
  15. Теплюк Н.П., Дороженок И.Ю., Катранова Д.Г. Истинная акантолитическая пузырчатка и коморбидные психосоматические расстройства: клиническая типология. Российский журнал кожных и венерических болезней. 2017; 20(4): 200-5.
  16. Дороженок И.Ю. Психические расстройства. Новая косметология. Методы косметологии в дерматологической практике. М.: Косметика и медицина; 2018: 444-57.
  17. Смулевич А.Б. Психосоматические расстройства (психопатология и клиническая систематика). Психосоматические расстройства в клинической практике. М.: Медпрессинформ; 2016: 23-39.

Copyright (c) 2019 Eco-Vector


 


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies