HISTORY OF VITILIGO EXPERIMENTAL STUDY


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Abstract

The history of the experimental study of vitiligo on animal models is studied. Effective analysis of any disease is not possible without conducting biomedical research on animal models. The models of both spontaneous and induced vitiligo in animals are described, which allows to study the etiology and pathogenesis of this disease in vivo, as well as to investigate the effectiveness of various drugs.

About the authors

Konstantin M. Lomonosov

Skin and Veneral desease Department of I.M. Sechenov First Moscow State Medical University

Email: lamсlinic@yandex.ru
MD, PhD, DSc, prof. I.M. Sechenov First Moscow State Medical University, Moscow, 119991, Russian Federation Moscow, 119991, Russian Federation

M. A Rem

Skin and Veneral desease Department of I.M. Sechenov First Moscow State Medical University

Moscow, 119991, Russian Federation

V. A Gorb

Skin and Veneral desease Department of I.M. Sechenov First Moscow State Medical University

Moscow, 119991, Russian Federation

References

  1. Goldman L., Moraites R.S., Kitzmiller K.W. White spots in biblical times. A background for the dermatologist for participation in discussions of current revisions of the bible. Arch. Dermatol. 1966; 93(6): 744-53.
  2. Seltenhammer M., Simhoter H., Scherzer S., Zechner P., Curik I., Sölkner J., et al. Equine melanoma in a populations of 296 grey Lipizzaner horses. Equine Vet. J. 2003; 35(2): 153-7.
  3. Naughton G.K., Mahaffey M., Bystrun J.C. Antibodies to surface antigens of pigmented cells in animals with vitiligo. Proc. Soc. Exp. Biol. Med. 1986; 181(3): 423-6.
  4. Pielberg G., Mikko S., Sanberg K., Andersson L. Comparative linkage mapping of the Grey coat color gene in horses. Anim. Gent. 2005; 36(5): 390-5.
  5. Lane C., Leitch J., Tan X., Hadjati J., Bramson J.L., Wan Y. Vaccination-induced autoimmune vitiligo is a consequence of secondary trauma to the skin. Cancer Res. 2004; 64(4): 1509-14.
  6. Pathak S., Multani A., McConkey D., Imam A.S., Amoss M.S. Spontaneous regression of cutaneous melanoma in Sinclain swine is associated with defective telomerase activity and extensive telomere erosion. Int. J. Oncol. 2000; 17(6): 1219-24.
  7. Cerundolo R., De Caprariis D., Esposito L., Maiolino P., Restucci B., Roperto F. Vitiligo in two water buffaloes: histological, histochemical and ultrastructural investigations. Pigment Cell Res.1993; 6(1): 23-8.
  8. Zavadskii V.N., Khovanova E.M. An experimental study of the morphogenetic properties of several phenols inducing phenocopies of vitiligo. Genetika. 1975; 11(2): 132-9.
  9. Smyth J.R.Jr. The Smyth chicken: a model for autoimmune amelanosis. Poult. Biol. 1989; 2: 1-19.
  10. Rezaei N., Gavalas N.G., Weetman A.P., Kemp E.H. Autoimmunity as an aetiological factor in vitiligo. J. Eur. Acad. Dermatol. Venereol. 2007; 21(7): 865-76.
  11. Erf G.F., Wijesekera H.D., Lockhart B.R., Golden A.L. Antioxidant capacity and oxidative stress in the local environment of feather-melanocytes in vitiliginous Smyth line chickens. Pigment Cell Res. 2005; 18(Suppl. 1): 69.
  12. Rosenthal N., Brown S. The mouse ascending: perspectives for human-disease models. Nat. Cell Biol. 2007; 9(9): 993-9.
  13. Lerner A.B., Shiohara T., Boissy R.E., Jacobson K.A., Lamoreux M.L., Moellmann G.E. A mouse model for vitiligo. J. Invest. Dermatol. 1986; 87(3): 299-304.
  14. Manga P., Orlov S. Engineering a new mouse model for vitiligo. J. Invest. Dermatol. 2012; 132(7): 1752-5.
  15. Harris J.E., Harris T.H., Weninger W., Wherry E.J., Hunter C.A., Turka L.A. A mouse model of vitiligo with focused epidermal depigmentation requires IFNγ for autoreactive CD8+ T-cell accumulation in the skin. J. Invest. Dermatol. 2012; 132(7): 1869-76. doi: 10.1038/jid.2011.463.
  16. You S., Cho Y., Byun J., Shin E. Melanocyte-specific CD8+ T cells are associated with epidermal depigmentation in a novel of vitiligo. Clin. Exp. Immunol. 2013; 174(1): 38-44.
  17. Jalel A., Soumaya G.S., Hamdaoui M.H. Vitiligo treatment with vitamins, minerels and polyphenol supplementation. Indian J. Dermatol. 2009; 54(4): 357-60.
  18. Agarwal P., Rashighi M., Essien K., Richmond J.M., Randall L., Pazoki-Toroudi H., et al. Simvastatin prevents and reverses depigmentation in a mouse model of vitiligo. J. Invest. Dermatol. 2015; 135(4): 1080-8.
  19. Huo S.X., Liu X.M., Ge C.H., Gao L., Peng X.M., Zhao P.P., Yan M. The effects of galangin on a mouse model of vitiligo induced by hydroquinone. Phytother. Res. 2014; 28(10): 1533-8.
  20. Huo S.X., Wang Q., Liu X.M., Ge C.H., Gao L., Peng X.M., Yan M. The effect of butin on the vitiligo mouse model induced by hydroquinone. Phytother. Res. 2017; 31(5): 740-6.

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