HYPERPIGMENTATION OF THE SKIN: MODERN VIEWS ON ETIOLOGY AND PATHOGENESIS (PART 1)


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Abstract

Brief literature review of the etiology and pathogenesis of hyperpigmentation on the basis of modern scientific publications is presented. The review focuses on actively studied mechanisms of melanin synthesis in norm and pathology, the physiology of pigment cells (melanocytes), their interaction with other structures of the epidermis and dermis and on the mechanisms of regulation of melanogenesis. The main factors influencing the appearance of hyperpigmentation are described.

About the authors

L. S Kruglova

Central State Medical Academy of General Management Department of the President of the Russian Federation

Moscow, 121359, Russian Federation

E. V Ikonnikova

Central State Medical Academy of General Management Department of the President of the Russian Federation

Email: evikonnikova@bk.ru
assistant, the department of dermatology and cosmetology of Central State Medical Academy of General Management Department of the President of the Russian Federation, Moscow, 121359, Russian Federation Moscow, 121359, Russian Federation

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