Interactions between the immune system disorders and intestinal microbios in patients with pityriasis versicolor


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Abstract

The immune system depending on the degree of intestinal microbiocenosis disorders in patients with pityriasis versicolor was investigated. Patients with pityriasis versicolor have an immune system disorder, which is expressed by a decrease in the activity of cellular immune system and enhancement of humoral one. In addition, in most cases of the pityriasis versicolor there are disbiotic changes, that contribute to the long-term course of the disease and are difficult to treat. The different changes in the immune system depending on the severity of intestinal disbiotic changes in patients with pityriasis versicolor were shown. It was revealed that in patients with pityriasis versicolor changes in the immune system are in direct proportion to the severity of disbiosis. It is appropriate to take into account these changes in the selection of treatment strategy ofpatients with pityriasis versicolor.

About the authors

Maruf R. Makhsudov

Republican Specialized Scientific and Practical Medical Center of Dermatology and Venereology

Email: bbh72@mail.ru
junior researcher Republican specialized research-and-practical medical center of Dermatology and Venerology Ministry of Health of the Republic of Uzbekistan Tashkent, Republic Uzbekistan

U. A Mamatkulov

Republican Specialized Scientific and Practical Medical Center of Dermatology and Venereology

Tashkent, Republic Uzbekistan

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