Review of pathogenetic mechanisms and methods for scar correction of cicatrices


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Abstract

The choice of an adequate methodfor the treatment of scar remains a challogingproblem. The pathogenesis of this process is still not known except that genetic liability, hyperproduction of growth factors, specifically, of transforming growth factor ft, imbalance between matrix metalloproteinases and their inhibitors are involved in scar formation. Drug therapy, spa therapy, and surgery are now usedfor correction scar; however, despite the numerous relevant methods, the problem remains unsolved.

About the authors

Ekaterina Yu. Vertieva

I.M. Setchenov First Moscow State Medical University

Email: ivertieva@gmail.com
MD, PhD 119991, Moscow, Russian Federation

O. Yu Olisova

I.M. Setchenov First Moscow State Medical University

Email: olisovaolga@mail.ru
Кафедра кожных и венерических болезней и Научно-образовательный клинический центр иммунозависимых дерматозов; доктор мед. наук, профессор 119991, Moscow, Russian Federation

N. G Kochergin

I.M. Setchenov First Moscow State Medical University

Email: nkocha@yandex.ru
Кафедра кожных и венерических болезней и Научно-образовательный клинический центр иммунозависимых дерматозов; доктор мед. наук, профессор 119991, Moscow, Russian Federation

I. Ya Pinson

I.M. Setchenov First Moscow State Medical University

Кафедра кожных и венерических болезней и Научно-образовательный клинический центр иммунозависимых дерматозов; доктор мед. наук, профессор, ведущий научный сотрудник 119991, Moscow, Russian Federation

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