Role of sexually transmitted infections in the development of female infertility. Therapeutic and preventive strategies

Sexually transmitted infections (STI) often become the cause of organic obstruction of the uterine tubes. Multicomponent mechanisms of sterility formation in young women under conditions of inflammatory diseases of the pelvic organs, detected in 60--65% women of reproductive age, are described. The spectrum of genital infections, detected by PCR analysis of discharge from the cervical canal and uterine cavity from women with chronic endometritis, includes chlamydiasis (in 14.9% patients), genital herpes (33.6%), ureaplasmosis (37.8%), mycoplasmosis (11.6%), and cytomegalovirus infection (18.9%). Today the clinical picture of many STD is blurred, and the main clinical sign of a chronic disease in young women is often disordered reproductive function, presented by sterility, including failure of repeated extracorporeal fertilization. Addition of longidase to combined therapy for sterility of different origin led to good results.

chlamydiasis, genital herpes, ureaplasmosis, mycoplasmosis, cytomegalovirus infection, inflammatory diseases of pelvic organs, tuboperitoneal sterility, chronic endometritis, extracorporeal fertilization, longidase in combined therapy and prevention of sterility