Modern aspects of effective therapy acne vulgaris


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Abstract

Today the diagnosis of acne severity is not limited by evaluation of clinical manifestations only. Therefore, indications for isotretinoin therapy of the dermatosis have been extended. We evaluated the efficiency and safety of Sotret in therapy of 30 patients with severe acne and with acne resistant to other therapies. Of these, 19 patients (63.33%) presented with mild-severety and 11 (36.67%) with severe condition. The acne dermatological index (ADI) and CADI score were evaluated and biochemical and clinical blood analyses were carried out in all patients. Sotret monotherapy was carried out. The clinical remission was attained in 28 (93.33%), and slight amelioration in 2 (6.67%) patients. Sotret therapy proved to be highly effective and was well tolerated.

About the authors

Yu. N Perlamutrov

A.I. Evdokimov Moscow State Medical Stomatological University

Кафедра кожных и венерических болезней; доктор мед. наук, профессор 127006, Moscow, Russia

Kira B. Olkhovskaya

A.I. Evdokimov Moscow State Medical Stomatological University

Email: olhovskaya_kira@mail.ru
MD, PhD, docent 127006, Moscow, Russia

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