Clovate therapy of steroid-sensitive dermatoses


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Abstract

The choice of a topical corticosteroid drug is a difficult problem for practical physician. Modern topical glucocorticosteroids are the most effective, as they unite the positive characteristics of previous drugs, their activity is comparable to that of fluorinated glucocorticoids, and their untoward effects (characteristic of hydrocortisone acetate) are the minimum. It is a class of modern potent drugs. One of them is Clovate® (active substance 0.05% clobethasol propionate; "Valeant", Canada). Prescription of a short course of Clovate during exacerbation and progress of severe psoriasis forms is safe and not associated with subclinical signs of augmenting adrenosuppression. "Step-down" therapy leads to a rapid clinical effect without side effects. Experience gained in the use of this method is presented.

About the authors

Elena S. Snarskaya

I.M. Setchenov First Moscow State Medical University

Email: snarskaya-dok@mail.ru
MD, PhD, DSc, prof. 119991, Moscow, Russia

L. M Shnakhova

I.M. Setchenov First Moscow State Medical University

Кафедра кожных и венерических болезней ИПО; ассистент 119991, Moscow, Russia

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