HIGH CONCENTRATION OF 3β-HYDROXYSTEROID DEHYDROGENASE IN SKIN CELLS OF PATIENTS WITH ACNE VULGARIS
- Authors: Bagrets A.N1, Kuznetsov V.A1, Ruksha T.G1
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Affiliations:
- V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
- Issue: Vol 16, No 5 (2013)
- Pages: 62-64
- Section: Articles
- URL: https://journals.rcsi.science/1560-9588/article/view/36884
- DOI: https://doi.org/10.17816/dv36884
- ID: 36884
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Abstract
The synthesis of testosterone is catalyzed by 3β-hydroxysteroid dehydrogenase. The development of acne is partialy associated with androgen-mediated hyperplasia of the sebaceous glands. The distribution and concentrations of 3β-hydroxysteroid dehydrogenase in the skin were studied in patients with acne. The results indicated hyperexpression of 3β-hydroxysteroid dehydrogenase in sebocytes, this presumably indicating disorders of the steroid metabolism in acne skin.
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##article.viewOnOriginalSite##About the authors
A. N Bagrets
V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
Email: bagrets@mail.ru
аспирант
V. A Kuznetsov
V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
Email: kuz.v90@mail.ru
студент
T. G Ruksha
V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
Email: tatyana_ruksha@mail.ru
доктор мед. наук
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