Email this article DIAGNOSTIC SIGNIFICANCE OF OSTEOCALCIN IN LEPROUS OSTEODESTRUCTIVE COMPLICATIONS
- Authors: Degtyarev O.V1, Sazykina U.A2, Lazareva E.N1
-
Affiliations:
- Astrakhan State Medical Academy
- Institute of Lepra
- Issue: Vol 16, No 5 (2013)
- Pages: 54-56
- Section: Articles
- URL: https://journals.rcsi.science/1560-9588/article/view/36872
- DOI: https://doi.org/10.17816/dv36872
- ID: 36872
Cite item
Full Text
Abstract
Osteocalcin protein was measured in leprous patients with osteodestructive complications and in the reference group of patients with other diseases. Osteocalcin concentrations were higher than normally in both groups, but to a different degree. The concentrations of this protein were significantly higher in leprous patients with osteodestructive changes. A 10-fold elevation of serum osteocalcin concentrations indicated destructive changes in bone tissue.
Keywords
Full Text
##article.viewOnOriginalSite##About the authors
O. V Degtyarev
Astrakhan State Medical Academy
Email: niil@astmail.astranet.ru
Department of Dermatovenereology
U. A Sazykina
Institute of Lepra
Email: sazikina.ulyana@yandex.ru
аспирант
E. N Lazareva
Astrakhan State Medical AcademyDepartment of Infectious Diseases
References
- Информационный бюллетень ВОЗ № 101. Женева; 2010.
- Анохина В.В., Урляпова Н.Г. Инвалидизирующие последствия у больных лепрой. В кн.: Материалы международной научно-практической конференции, посвященной 60-летию института и 85-летию противолепрозной службы России. Астрахань; 2008: 92—9.
- Минченко Б.И., Беневоленский Д.С., Тишенина Р.С. Биохимические показатели метаболических нарушений в костной ткани. Ч. 1. Резорбция кости. Клиническая лабораторная диагностика. 1999; 1: 8—15.
- Garnero P., Sornay-Rendu E., Chapuy M., Delmas P.D. Increased bone turnover in late postmenopausal women is a major determinant of osteoporosis. J. Bone Miner. Res. 1996; 11(3): 337—49.
- Masters P.W., Jones R.G., Purves D.A., Cooper E.H., Cooney J.M. Commercial assays for serum osteocalcin give clinically discordant results. Clin. Chem. 1994; 40(3): 358—63.
- Гланс С. Медико-биологическая статистика. М.: Практика; 1999.
- Ishikawa A., Ishikawa S., Hirakawa M. Osteoporosis, bone turnover and hypogonadism in elderly men with treated leprosy. Lepr. Rev. 2001; 72(3): 322—9.
