Novel approaches to psoriatic onychopathy diagnostics and treatment
- 作者: Zdzitovetskaya N.D.1, Karacheva Y.V.1, Ruksha T.G.1
-
隶属关系:
- Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
- 期: 卷 27, 编号 3 (2024)
- 页面: 340-347
- 栏目: DERMATOLOGY
- URL: https://journals.rcsi.science/1560-9588/article/view/262725
- DOI: https://doi.org/10.17816/dv569042
- ID: 262725
如何引用文章
详细
Psoriasis is one of the most important problems in the clinical practice of a dermatovenereologist. In addition to damage of the skin and joints, the nail involvement is often seen in psoriatic patients. Despite its wide prevalence and significant impact on the quality of life, psoriatic onychopathy is discussed relatively rare. A change in the nails may indicate early alterations in the small joints of the palms, еthat foster to suspect psoriatic arthritis at an earlier time. Besides, the severity of nails lesions determined on the base of the NAPSI index correlates directly with the severity of pain in enthesitis.
Nails damage in psoriasis does not entail persistent functional disorders, but significantly affects the patient’s quality of life due to a visible cosmetic defect. In addition, psoriatic onychopathy is difficult to treat. The use of topical agents is impractical, and systemic therapy gives a weak clinical response over a longer period. Even in the absence of a pathological process on the skin, nail psoriasis may persist much longer, which causes significant discomfort to patients.
The study of pathomorphological aspects and mechanisms of nail psoriasis development will allow to disover a new methods for the effective treatment of psoriatic onychopathy.
作者简介
Natalia Zdzitovetskaya
Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
Email: nzdzit100195@gmail.com
ORCID iD: 0000-0002-2976-8748
SPIN 代码: 7685-4887
俄罗斯联邦, Krasnoyarsk
Yulia Karacheva
Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
Email: julkar19@yandex.ru
ORCID iD: 0000-0003-2619-9786
SPIN 代码: 4789-9178
MD, Dr. Sci. (Med.), Associate Professor
俄罗斯联邦, KrasnoyarskTatiana Ruksha
Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
编辑信件的主要联系方式.
Email: tatyana_ruksha@mail.ru
ORCID iD: 0000-0001-8142-4283
SPIN 代码: 5412-2148
MD, Dr. Sci. (Med.), Professor
俄罗斯联邦, Krasnoyarsk参考
- Kaeley GS, Eder L, Aydin SZ, et al. Nail psoriasis: Diagnosis, assessment, treatment options, and unmet clinical needs. J Rheumatol. 2021;48(8):1208–1220. doi: 10.3899/jrheum.201471
- Canal-García E, Bosch-Amate X, Belinchón I. Psoriasis ungueal. Actas Dermosifiliogr. 2022;113(5):481–490. doi: 10.1016/j.ad.2022.01.006
- Pasch MC. Nail psoriasis: A review of treatment options. Drugs. 2016;76(6):675–705. doi: 10.1007/s40265-016-0564-5
- Folle L, Fenzl P, Fagni F, et al. DeepNAPSI multi-reader nail psoriasis prediction using deep learning. Sci Rep. 2023;13(1):5329. doi: 10.1038/s41598-023-32440
- Arora S, Debatraya P, Richa K. Study of nail psoriasis and dermoscopic correlation with dermoscopic and modified dermoscopic nail psoriasis severity indexes (dNAPSI and dmNAPSI). Dermatol Pract Conceptua. 2022;12(1):e2022010. doi: 10.5826/dpc.1201a10
- Platonova AV, Zhukov AS, Khairutdinov VR, Samtsov AV. Psoriatic onychodystrophy: Indices for assessing the severity of psoriatic onychodystrophy (part 2). Vestnik dermatologii i venerologii. 2019;95(1):9–14. EDN: SOEDZJ doi: 10.25208/0042-4609-2019-95-1-9-14
- Morrison AV, Ardalina OO, Moiseev AA, Eldesbayeva YS. Acrodermatitis of hallopeau (clinical case). Saratov J Med Sci Res. 2022;18(4):723–725. EDN: VLBAAU
- Long FY, Zhang ZQ, He F, et al. Dermoscopic features of nail psoriasis: Positive correlation with the severity of psoriasis. Int J Dermatol. 2021;48(6):894–901. doi: 10.1111/1346-8138.15908
- Lee DK, Lipne SR. Optimal diagnosis and management of common nail disorders. Ann Med. 2022;54(1):694–712. doi: 10.1080/07853890.2022.2044511
- Coates LC, Soriano ER, Corp N, et al.; the GRAPPA Treatment Recommendations domain subcommittees. Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA): Updated treatment recommendations for psoriatic arthritis 2021. Nat Rev Rheumatol. 2022;18(8):465–479. doi: 10.1038/ s41584-022-00798-0
- Mease PJ, Liu M, Rebello S, et al. Association of nail psoriasis with disease activity measures and impact in psoriatic arthritis: Data from the corrona psoriatic arthritis/spondyloarthritis registry. J Rheumatol. 2021;48(4):520–526. doi: 10.3899/jrheum.190923
- Sidorcik TG, Linev VA, Radzina MA, et al. Thesitis and psoriatic onychopathy as a factor for prediction of psoriatic arthritis in psoriasis. Vestnik dermatologii i venerologii. 2018;(1):38–50. EDN: UNYVCL doi: 10.25208/0042-4609-2018-94-1-38-50
- Platonova AV, Zhukov AS, Volkov KY, et al. The prevalence incidence of psoriatic onychodystrophy and the significance of its symptoms for the diagnosis of psoriatic arthritis. Vestnik dermatologii i venerologii. 2021;97(6):63–69. EDN: LLHHBI doi: 10.25208/vdv1262
- Draghi F, Ferrozzi G, Ballerini D, Bortolotto C. Psoriatic arthritis: Ultrasound peculiarities with particular emphasis on enthesitis. J Clin Ultrasound. 2022;50(4):556–560. doi: 10.1002/jcu.23170
- Choo ZN, Lipner SR. Onychogryphosis is associated with dermatologic and vascular disease: A case-control study of the all of us research program. Skin Appendage Disord. 2023;9(4):252–257. doi: 10.1159/000530096
- Olisova OY, Faranyan LG. The prevalence of co-morbidities in Russian patients with psoriasis: A retrospective study. Res J Pharmaceutica, Biological Chemical Sci. 2019;10(1):797–800. EDN: GHTWTD
- Platonova AV, Zhukov AS, Khairutdinov VR, Samtsov AV. Clinical and morphological characteristics of psoriatic onychodystrophy. Russ Military Med Acad Rep. 2020;39(S3-3):166–171. EDN: HEQLYM
- Kyriakou A, Zagalioti SC, Trakatelli MG, et al. Fungal infections and nail psoriasis: An update. J Fungi. 2022;8(2):154. doi: 10.3390/jof8020154
- Hwang JK, Grover C, Iorizzo M, et al. Nail psoriasis and nail lichen planus: Updates on diagnosis and management. J Am Acad Dermatol. 2023:90(3):585−596. doi: 10.1016/j.jaad.2023.11.024
- Hwang JK, Ricardo JW, Lipner SR. Efficacy and safety of nail psoriasis targeted therapies: A systematic review. Am J Clin Dermatol. 2023;24(5):695–720. doi: 10.1007/s40257-023-00786-4
- Rigopoulos D, Baran R, Chiheb S, et al. Recommendations for the definition, evaluation, and treatment of nail psoriasis in adult patients with no or mild skin psoriasis: A dermatologist and nail expert group consensus. J Am Acad Dermatol. 2019;81(1):228−240. doi: 10.1016/j.jaad.2019.01.072
- Al Ajlan A, Qasim R, Al Tassan F, et al. A case of nail psoriasis improved with treatment by Risankizumab. Oxford Med Case Rep. 2022;(11):omac127. doi: 10.1093/omcr/omac127
- Haneke E. Nail psoriasis: clinical features, pathogenesis, differential diagnoses, and management. Psoriasis (Auckl). 2017;(7):51–63. doi: 10.2147/PTT.S126281
- Tosti A, Ricotti C, Romanelli P, et al. Evaluation of the efficacy of acitretin therapy for nail psoriasis. Arch Dermatol Res. 2009;145(3):269−271. doi: 10.1001/archdermatol.2008.600
- Battista T, Scalvenzi M, Martora F, et al. Nail psoriasis: An updated review of currently available systemic treatments. Clin Cosmet Investig Dermatol. 2023:(16):1899−1932. doi: 10.2147/CCID.S417679
- Krajewska-Włodarczyk M, Zuber Z, Owczarczyk-Saczonek A. Ultrasound evaluation of the effectiveness of the use of acitretin in the treatment of nail psoriasis. J Clin Med. 2021;10(10):2122. doi: 10.3390/jcm10102122
- Azuaga AB, Ramirez J, Canete JD. Psoriatic arthritis: Pathogenesis and targeted therapies. Int J Mol Sci. 2023;24(5):4901. doi: 10.3390/ijms24054901
- Bardazzi F, Starace M, Bruni F, et al. Nail psoriasis: An updated review and expert opinion on available treatments, including biologics. Acta Derm Venereol. 2019;99(6):516–523. doi: 10.2340/00015555-3098
- Murashkin NN, Materikin AI, Ambarchian ET, et al. Psoriasis and psoriatic arthritis in childhood. Curr Pediatr. 2020;19(6):444–451. EDN: JAWLDQ doi: 10.15690/vsp.v19i6.2146
- Namazova-Baranova LS, Murashkin NN, Ambarchian ET, Materikin AI. Systemic psoriasis treatment at an early age (part 2): Issues of biological therapy. Vestnik dermatologii i venerologii. 2017;(6):100–107. EDN: YQGQOC doi: 10.25208/0042-4609-2017-93-6-100-107
- Kirkham BW, Egeberg A, Behrens F, et al. A Comprehensive review of ixekizumab efficacy in nail psoriasis from clinical trials for moderate-to-severe psoriasis and psoriatic arthritis. Rheumatol Ther. 2023;10(5):1127–1146. doi: 10.1007/s40744-023-00553-1
- Stewarta CR, Rakhshan LA, Kamranc R, et al. The impact of nail psoriasis and treatment on quality of life: A systematic review. Skin Appendage Disord. 2021;7(2):83–89. doi: 10.1159/000512688
- Rich P, Goldblum O, Disch D, et al. Nail psoriasis does not affect skin response to ixekizumab in patients with moderate-to-severe psoriasis. J Drugs Dermatol. 2020;19(8):741−746. doi: 10.36849/JDD.2020.5116
- Reich K, Sullivan J, Arenberger J, et al. Secukinumab shows high and sustained efficacy in nail psoriasis: 2.5-year results from the randomized placebo-controlled TRANSFIGURE study. Brit J Dermatol. 2021;184(3):425−436. doi: 10.1111/bjd.19262
- Loginova EYu, Korsakova YuL, Korotaeva TV. Experience of guselkumab usage in the treatment of patients with psoriatic arthritis in real clinical practice. Modern Rheumatol J. 2021;15(5):89–95. EDN: IHLBQC doi: 10.14412/1996- 7012-2021-5-89-95
- Wang N, Yang Q, Liu Yo, Liu H. Upadacitinib in nail psoriasis: A case report. J Dermatol Treat. 2023;34(1):2246604. doi: 10.1080/09546634.2023.2246604
- Iorizzo M, Tosti A. Updates in treatment and impact of nail psoriasis. Expert Rev Clin Immunol. 2023;19(9):1091–1100. doi: 10.1080/1744666X.2023.2215987
- Nirbhavane P, Sharma G, Verma S, et al. Nail psoriasis treatment: Insights into current progress and future trends. Crit Rev Ther Drug Carrier Syst. 2020;37(2):135–159. doi: 10.1615/CritRevTherDrugCarrierSyst.2020029259
- Thomas L, Azad J, Takwale A. Management of nail psoriasis. Clin Exp Dermatol. 2021;46(1):3−8. doi: 10.1111/ced.14314
- Buhas MC, Candrea R, Gavrilas LI, et al. Transforming psoriasis care: Probiotics and prebiotics as novel therapeutic approaches. Int J Mol Sci. 2023;24(13):11225. doi: 10.3390/ijms241311225
- Augustin M, Blome C, Costanzo A, et al. Nail Assessment in Psoriasis and Psoriatic Arthritis (NAPPA): Development and validation of a tool for assessment of nail psoriasis outcomes. Brit J Dermatol. 2014;170(3):591−598. doi: 10.1111/bjd.12664
补充文件
