Email this article Epidemic season 2021–2022: Frequency of co-infection by respiratory viral pathogens
- Authors: Burtseva E.I.1, Panova A.D.1, Kolobukhina L.V.1, Ignatjeva A.V.1, Kirillova E.S.1, Breslav N.V.1, Trushakova S.V.1, Mukasheva E.A.1, Feodoritova E.L.1, Krasnoslobodtsev K.G.1, Merkulova L.N.1, Khlopova I.N.1, Kisteneva L.B.1, Kruzhkova I.S.1, Levochkina Y.S.1,2, Krepkaia A.S.1, Rosatkevich A.G.1, Komissarov A.B.3, Yatsishina S.B.4, Pochtovyi A.A.1, Kustova D.D.1, Gushchin V.A.1, Bazarova M.V.5, Smetanina S.V.5, Tsvetkova N.A.2
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Affiliations:
- National Research Centre of Epidemiology and Microbiology
- Clinical Hospital for Infectious Diseases № 2
- Research institute of influenza
- Central Research institute of epidemiology of Rospotrebnadzor
- Clinical Hospital for Infectious Diseases № 1
- Issue: Vol 28, No 2 (2023)
- Pages: 67-77
- Section: ORIGINAL STUDIES
- URL: https://journals.rcsi.science/1560-9529/article/view/131258
- DOI: https://doi.org/10.17816/EID321873
- ID: 131258
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Abstract
BACKGROUND: This study was conducted to determine the characteristics of various viral respiratory pathogens spreading during the epidemic season 2021–2022 and the frequency of co-infection with SARS-CoV-2 and influenza.
AIM: To assess the development of the influenza epidemic and frequency of cases of co-infection with respiratory pathogens in patients with acute respiratory viral infections between 2021 and 2022.
MATERIALS AND METHODS: Traditional and hospital epidemiological surveillance methods for acute respiratory viral infections were used.
RESULTS: The epidemic season of 2021–2022 was characterized by the early activity of the influenza A(H3N2) virus and the emergence and rapid spread of the omicron variant of SARS-CoV-2. The distribution of different respiratory pathogens during the epidemic season 2021–2022 was clearly traced: SARS-CoV-2 (18.8%) was predominant, followed by influenza viruses (10.6%) and pathogens of other acute respiratory viral infections (0.4–3.7%). With respect to influenza A (H3N2) and B viruses, the heterogeneity of their populations and drift variability in relation to vaccine strains were noted.
DISCUSSION: The frequency of co-infection with various respiratory pathogens was low, i.e., it was no more than 0.1%according to traditional surveillance, and no more than 9.2% in the hospital surveillance. The rationale for updating the composition of influenza vaccines for the countries in the Northern Hemisphere for 2022–2023 season was identified.
CONCLUSION: At present, early diagnosis of influenza is important given the availability of effective drugs with a direct mechanism of action for the prevention and treatment of this pathogen. Timely use of anti-influenza drugs will reduce the risks of a severe course, complications, and death, including co-infection with SARS-CoV-2.
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##article.viewOnOriginalSite##About the authors
Elena I. Burtseva
National Research Centre of Epidemiology and Microbiology
Author for correspondence.
Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0003-2518-6801
SPIN-code: 2707-1446
MD, Dr. Sci (Med.)
Russian Federation, MoscowAnna D. Panova
National Research Centre of Epidemiology and Microbiology
Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0002-9322-6273
Russian Federation, Moscow
Ludmila V. Kolobukhina
National Research Centre of Epidemiology and Microbiology
Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0001-5775-3343
Russian Federation, Moscow
Anna V. Ignatjeva
National Research Centre of Epidemiology and Microbiology
Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0001-6206-2299
Russian Federation, Moscow
Elena S. Kirillova
National Research Centre of Epidemiology and Microbiology
Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0001-7977-7530
Russian Federation, Moscow
Natalia V. Breslav
National Research Centre of Epidemiology and Microbiology
Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0002-6946-5119
Russian Federation, Moscow
Svetlana V. Trushakova
National Research Centre of Epidemiology and Microbiology
Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0002-9610-3041
Russian Federation, Moscow
Evgeniya A. Mukasheva
National Research Centre of Epidemiology and Microbiology
Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0002-5688-5309
Russian Federation, Moscow
Elena L. Feodoritova
National Research Centre of Epidemiology and Microbiology
Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0002-1472-1357
Russian Federation, Moscow
Kirill G. Krasnoslobodtsev
National Research Centre of Epidemiology and Microbiology
Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0003-1745-9128
Russian Federation, Moscow
Liliya N. Merkulova
National Research Centre of Epidemiology and Microbiology
Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0002-7260-0879
Russian Federation, Moscow
Irina N. Khlopova
National Research Centre of Epidemiology and Microbiology
Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0002-7419-590X
Russian Federation, Moscow
Lidiya B. Kisteneva
National Research Centre of Epidemiology and Microbiology
Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0001-7336-409X
Russian Federation, Moscow
Irina S. Kruzhkova
National Research Centre of Epidemiology and Microbiology
Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0002-1983-481X
Russian Federation, Moscow
Yuliya S. Levochkina
National Research Centre of Epidemiology and Microbiology; Clinical Hospital for Infectious Diseases № 2
Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0002-7750-2311
Russian Federation, Moscow; Moscow
Anastasia S. Krepkaia
National Research Centre of Epidemiology and Microbiology
Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0002-7272-4011
Russian Federation, Moscow
Aleksandra G. Rosatkevich
National Research Centre of Epidemiology and Microbiology
Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0003-0008-8711
Russian Federation, Moscow
Andrey B. Komissarov
Research institute of influenza
Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0003-1733-1255
Russian Federation, Saint Petersburg
Svetlana B. Yatsishina
Central Research institute of epidemiology of Rospotrebnadzor
Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0003-4737-941X
Russian Federation, Moscow
Andrey A. Pochtovyi
National Research Centre of Epidemiology and Microbiology
Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0003-1107-9351
Russian Federation, Moscow
Daria D. Kustova
National Research Centre of Epidemiology and Microbiology
Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0002-8382-275X
Russian Federation, Moscow
Vladimir A. Gushchin
National Research Centre of Epidemiology and Microbiology
Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0002-9397-3762
Russian Federation, Moscow
Marina V. Bazarova
Clinical Hospital for Infectious Diseases № 1
Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0001-7322-7896
Russian Federation, Moscow
Svetlana V. Smetanina
Clinical Hospital for Infectious Diseases № 1
Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0003-3763-697X
Russian Federation, Moscow
Natalia A. Tsvetkova
Clinical Hospital for Infectious Diseases № 2
Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0003-3323-3401
Russian Federation, Moscow
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