The case of food botulism F

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This case describes a rare case of food botulism F in a 42-year-old man, which developed after he ate dried fish. The disease proceeded in a severe form with the development of ophthalmoplegia, tetraparesis, and respiratory failure. Monovalent antitoxic serums against botulinum toxins A, B, and E were administered to the patient. However, on the third day of the disease, he developed fulminant toxic myocarditis with asystole. Despite successful resuscitation, the patient developed a post-resuscitation disease and anoxic encephalopathy. The disease was complicated by severe aspiration pneumonia caused by Klebsiella pneumoniae (ESBL+). The duration of mechanical ventilation was 12 days. His hemodynamics stabilized on the eighth day of illness, and on the 19th day of illness, physical activity and a state of minimal consciousness appeared. The patient was transferred to the rehabilitation department on the 22nd day of the illness.

Doctors should be informed about the possibility of the development and severity of botulism caused by botulinum toxin type F. It is necessary to introduce polyvalent antibotulinic serum into clinical practice, including antitoxins against rare types of botulinum toxin.

作者简介

Irina Nikolaeva

Kazan State Medical University

编辑信件的主要联系方式.
Email: irinanicolaeva@mail.ru
ORCID iD: 0000-0003-0104-5895
SPIN 代码: 4103-5663

MD, Dr Sci. (Med.), Professor

俄罗斯联邦, Kazan

Fayruza Gilmullina

Kazan State Medical University

Email: fayruza.gilmullina@yandex.ru
ORCID iD: 0000-0002-3015-8920
SPIN 代码: 8620-0710

MD, Cand. Sci. (Med.), Associate Professor

俄罗斯联邦, Kazan

Aleksander Kazancev

Republican Clinical Hospital of Infectious Diseases named after A.F. Agafonov

Email: engine90@bk.ru
ORCID iD: 0000-0001-9800-9940
SPIN 代码: 4888-8556

MD, Cand. Sci. (Med.)

俄罗斯联邦, Kazan

Bulat Fatkullin

Republican Clinical Hospital of Infectious Diseases named after A.F. Agafonov

Email: bulat.fatkullin.68@bk.ru
SPIN 代码: 8772-3423

MD, Cand. Sci. (Med.)

俄罗斯联邦, Kazan

参考

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  5. Hall JD, McCroskey LM, Pincomb BJ, Hatheway CL. Isolation of an organism resembling Clostridium barati which produces type F botulinal toxin from an infant with botulism. J Clin Microbiol. 1985;21(4):654–655. doi: 10.1128/jcm.21.4.654-655.1985
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  7. Gupta A, Sumner CJ, Castor M, Maslanka S, Sobel J. Adult botulism type F in the United States, 1981–2002. Neurology. 2005;65(11):1694–1700. doi: 10.1212/01.wnl.0000187127.92446.4c
  8. Moodley A, Quinlisk P, Garvey A, et al.; Centers for Disease Control and Prevention (CDC). Notes from the field: infant botulism caused by Clostridium baratii type F — Iowa, 2013. MMWR Morb Mortal Wkly Rep. 2015;64(14):400.
  9. Tréhard H, Poujol I, Mazuet C, et al. A cluster of three cases of botulism due to Clostridium baratii type F, France, August 2015. Euro Surveill. 2016;21(4). doi: 10.2807/1560-7917.ES.2016.21.4.30117
  10. Yu PA, Lin NH, Mahon BE, et al. Safety and Improved Clinical Outcomes in Patients Treated With New Equine-Derived Heptavalent Botulinum Antitoxin. Clin Infect Dis. 2017;66(Suppl. 1):S57–S64. doi: 10.1093/cid/cix816

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版权所有 © Nikolaeva I.V., Gilmullina F.S., Kazancev A.Y., Fatkullin B.S., 2022

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