Email this article Possibilities of modern methods of laboratory diagnostics in the study of viral hepatitis A
- Authors: Volchkova E.V.1, Belaya O.F.1, Umbetova K.T.1, Pshenichnaya N.Y.2, Malov V.A.1, Konnova Y.A.3
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Affiliations:
- The First Sechenov Moscow State Medical University
- Central Research Institute of Epidemiology
- Infectious diseases Hospital № 2
- Issue: Vol 25, No 6 (2020)
- Pages: 264-268
- Section: CASE REPORTS
- URL: https://journals.rcsi.science/1560-9529/article/view/82724
- DOI: https://doi.org/10.17816/EID82724
- ID: 82724
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Abstract
It is generally accepted that the course of viral hepatitis A is accompanied by short-term viremia, and the disease itself does not have serious consequences for the person who has recovered. The article describes a clinical case of a protracted course of viral hepatitis A with long-term persistence of the virus. Against the background of the therapy, the patient's condition improved, and by the time of discharge from the hospital on the 38th day of illness and later, with a retrospective examination on the 68th day from the onset of the disease by the method of reverse transcription PCR (RT-PCR in real time), the presence of RNA of the hepatitis A virus was confirmed in feces, which indicated a long persistence of the virus in the body. This observation indicates the need for long-term dispensary observation of patients who have undergone viral hepatitis A.
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##article.viewOnOriginalSite##About the authors
Elena V. Volchkova
The First Sechenov Moscow State Medical University
Email: antononina@rambler.ru
ORCID iD: 0000-0003-4581-4510
SPIN-code: 3342-4681
MD, Dr. Sci. (Med), Professor
Russian Federation, 8 bld. 2 Trubetskaya street, 119991, MoscowOlga F. Belaya
The First Sechenov Moscow State Medical University
Email: ofbelaya@mail.ru
ORCID iD: 0000-0002-2722-1335
SPIN-code: 3921-7227
MD, Dr. Sci. (Med.), Professor
Russian Federation, 8 bld. 2 Trubetskaya street, 119991, MoscowKarina T. Umbetova
The First Sechenov Moscow State Medical University
Email: karinasara@inbox.ru
ORCID iD: 0000-0003-0902-9267
SPIN-code: 3197-9205
MD, Dr. Sci. (Med.), Professor
Russian Federation, 8 bld. 2 Trubetskaya street, 119991, MoscowNatalia Y. Pshenichnaya
Central Research Institute of Epidemiology
Email: natalia-pshenichnaya@yandex.ru
ORCID iD: 0000-0003-2570-711X
SPIN-code: 5633-7265
MD, Dr. Sci. (Med.), Professor
Russian Federation, MoscowValerii A. Malov
The First Sechenov Moscow State Medical University
Email: valmalov@list.ru
ORCID iD: 0000-0002-6157-1654
SPIN-code: 4790-8986
MD, Dr. Sci. (Med.), Professor
Russian Federation, 8 bld. 2 Trubetskaya street, 119991, MoscowYulia A. Konnova
Infectious diseases Hospital № 2
Author for correspondence.
Email: konnova.yulia@gmail.com
ORCID iD: 0000-0003-3091-2433
SPIN-code: 7856-0880
MD, Cand. Sci. (Med.)
Russian Federation, MoscowReferences
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