Detection and analysis of integrative conjugative elements in Vibrio spp. strains, isolated in the Volgograd region


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Abstract

The presence of integrative conjugative elements (ICEs) of SXT/R391 family in different Vibrio species isolated from natural water sources in the Volgograd region in 2003 - 2014 was established. Trimethoprim (dfr18), streptomycin (strB) and sulfametoxazol (sulII) resistance genes were detected in ICEs pattern of in V. choleraenon-O1/non-O139 strains. In Vibrio spp. ICEs strains not referred to V. cholerae type there was detected another variant of dihydrofolate reductase gene - dfrA1 localized outside the main resistance cluster. The obtained results indicate to that aqueous Vibrio spp. strains may be potential reservoir of resistance genes.

About the authors

Irina B. Zakharova

Volgograd Plague Control Research Institute of the Federal Service for Surveillance in the Sphere of Consumers Rights Protection and Human Welfare

Email: zib279@gmail.com
MD, PhD, Head of the Laboratory of Genomics and Proteomics of the Volgograd Plague Control Research Institute of the Federal Service for Surveillance in the Sphere of Consumers Rights Protection and Human Welfare 7, Golubiskaya str., Volgograd, 400012, Russian Federation

Yu. A Kuzyutina

Volgograd Plague Control Research Institute of the Federal Service for Surveillance in the Sphere of Consumers Rights Protection and Human Welfare

науч. сотр. лаб. геномики и протеомики ФКУЗ Волгоградский научно-исследовательский противочумный институт Роспотребнадзора 7, Golubiskaya str., Volgograd, 400012, Russian Federation

M. V Podshivalova

Volgograd Plague Control Research Institute of the Federal Service for Surveillance in the Sphere of Consumers Rights Protection and Human Welfare

науч. сотр. лаб. геномики и протеомики ФКУЗ Волгоградский научно-исследовательский противочумный институт Роспотребнадзора 7, Golubiskaya str., Volgograd, 400012, Russian Federation

A. A Zamarin

Volgograd Plague Control Research Institute of the Federal Service for Surveillance in the Sphere of Consumers Rights Protection and Human Welfare

науч. сотр. лаб. геномики и протеомики ФКУЗ Волгоградский научно-исследовательский противочумный институт Роспотребнадзора 7, Golubiskaya str., Volgograd, 400012, Russian Federation

A. V Toporkov

Volgograd Plague Control Research Institute of the Federal Service for Surveillance in the Sphere of Consumers Rights Protection and Human Welfare

доктор мед. наук, директор ФКУЗ Волгоградский научноисследовательский противочумный институт Роспотребнадзора 7, Golubiskaya str., Volgograd, 400012, Russian Federation

D. V Viktorov

Volgograd Plague Control Research Institute of the Federal Service for Surveillance in the Sphere of Consumers Rights Protection and Human Welfare

доктор биол. наук, доцент, зам. директора по научно-экспериментальной работе ФКУЗ Волгоградский научно-исследовательский противочумный институт Роспотребнадзора 7, Golubiskaya str., Volgograd, 400012, Russian Federation

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