Changes in the phenotype and functional metabolic activity of immunocompetent blood cells in infants with Epstein-Barr virus infection


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Abstract

Sixty-eight patients aged 1-3 years, with infectious mononucleosis caused by Epstein-Barr virus infection, were followed up in the acute period of the disease. Cellular and humoral immunological parameters, the lymphocyte activity of NAD(P)-dependent dehydrogenases, the phagocytic activity, spontaneous and induced chemiluminescence of peripheral blood neutrophils were studied. Changes were found in the immunophenotypic spectrum and enzyme status of peripheral blood lymphocytes. Impairments were detected in the phagocytic activity and chemiluminescent response of neutrophils.

About the authors

Lyudmila Mikhaylovna Kurtasova

ГОУ ВПО Красноярский государственный медицинский университет им. проф. В. Ф. Войно-Ясенецкого

Email: aids@ktk.ru
д-р мед. наук, проф. каф. клин. иммунологииТелефон: (3912)27-24-13; ГОУ ВПО Красноярский государственный медицинский университет им. проф. В. Ф. Войно-Ясенецкого

A R Shmidt

Краевой центр по профилактике и борьбе со СПИДом, Красноярск

Краевой центр по профилактике и борьбе со СПИДом, Красноярск

L M Kurtasova

Prof. V. F. Voino-Yasenetsky Krasnoyarsk State Medical University

Prof. V. F. Voino-Yasenetsky Krasnoyarsk State Medical University

A R Shmidt

Territorial Center for AIDS Prevention and Control, Krasnoyarsk

Territorial Center for AIDS Prevention and Control, Krasnoyarsk

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