Noroviruses as an etiological factor of acute enteric infections in Novosibirsk infants


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Abstract

A total of 1007 fecal samples from the infants admitted to the unit of enteric infections, Children's City Clinical Hospital Three, Novosibirsk, were tested for genotypes 1 and 2 noroviruses in January to December 2006. It was ascertained that 12.4% of the samples contained noroviruses, most of the detected viruses being genotype 2 noroviruses (94.4%); noroviruses along with other viral pathogens were found in 7.2% of the samples. There was an age-related association - 70% of the noroviruses were isolated from infants aged 6 to 18 months. There was a morbidity rise in December 2006 when noroviruses were identified in 39% of the samples, which allowed them to hold the lead, by outstripping the traditionally more common rotavirus infection. Twenty norovirus isolates of noroviruses were tested for nucleotide sequence in the 5'-region of the gene encoding the capsid protein. The study isolates were shown to be very close and different in nucleotide sequence by not more than 4.5%.

About the authors

S A Bodnev

ФГУН Государственный научный центр вирусологии и биотехнологии "Вектор" Роспотребнадзора

ФГУН Государственный научный центр вирусологии и биотехнологии "Вектор" Роспотребнадзора

V V Maleev

Центральный НИИ эпидемиологии Роспотребнадзора

Центральный НИИ эпидемиологии Роспотребнадзора

E V Zhirakovskaya

ФГУН Государственный научный центр вирусологии и биотехнологии "Вектор" Роспотребнадзора

ФГУН Государственный научный центр вирусологии и биотехнологии "Вектор" Роспотребнадзора

T E Yun

ФГУН Государственный научный центр вирусологии и биотехнологии "Вектор" Роспотребнадзора

ФГУН Государственный научный центр вирусологии и биотехнологии "Вектор" Роспотребнадзора

A Yu Tikunov

ФГУН Государственный научный центр вирусологии и биотехнологии "Вектор" Роспотребнадзора

ФГУН Государственный научный центр вирусологии и биотехнологии "Вектор" Роспотребнадзора

N A Nikiforova

МУЗ Детская городская клиническая больница № 3

МУЗ Детская городская клиническая больница № 3

T G Korsakova

МУЗ Детская городская клиническая больница № 3

МУЗ Детская городская клиническая больница № 3

V V Klemesheva

МУЗ Детская городская клиническая больница № 3

МУЗ Детская городская клиническая больница № 3

A V Kachko

ФГУН Государственный научный центр вирусологии и биотехнологии "Вектор" Роспотребнадзора

ФГУН Государственный научный центр вирусологии и биотехнологии "Вектор" Роспотребнадзора

A T Podkolzin

Центральный НИИ эпидемиологии Роспотребнадзора

Центральный НИИ эпидемиологии Роспотребнадзора

Nina Viktorovna Tikunova

ФГУН Государственный научный центр вирусологии и биотехнологии "Вектор" Роспотребнадзора

Email: vector@vector.nsc.ru
д-р биологических наук, доц., зав. лаб. разработки средств экстренной профилактики ФГУН Государственный научный центр вирусологии и биотехнологии "Вектор" Роспотребнадзора; ФГУН Государственный научный центр вирусологии и биотехнологии "Вектор" Роспотребнадзора

S A Bodnev

"Vektor" State Research Center of Virology and Biotechnology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

"Vektor" State Research Center of Virology and Biotechnology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

V V Maleyev

Central Research Institute of Epidemiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

Central Research Institute of Epidemiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

Ye V Zhirakovskaya

"Vektor" State Research Center of Virology and Biotechnology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

"Vektor" State Research Center of Virology and Biotechnology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

T E Yun

"Vektor" State Research Center of Virology and Biotechnology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

"Vektor" State Research Center of Virology and Biotechnology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

A Yu Tikunov

"Vektor" State Research Center of Virology and Biotechnology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

"Vektor" State Research Center of Virology and Biotechnology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

N A Nikiforova

Children's City Clinical Hospital Three

Children's City Clinical Hospital Three

T G Korsakova

Children's City Clinical Hospital Three

Children's City Clinical Hospital Three

V V Klemesheva

Children's City Clinical Hospital Three

Children's City Clinical Hospital Three

A V Kachko

"Vektor" State Research Center of Virology and Biotechnology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

"Vektor" State Research Center of Virology and Biotechnology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

A T Podkolzin

Central Research Institute of Epidemiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

Central Research Institute of Epidemiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

N V Tikunova

"Vektor" State Research Center of Virology and Biotechnology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

"Vektor" State Research Center of Virology and Biotechnology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

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