A case of amebiasis with multiple liver abscesses: A way to diagnosis

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Abstract

Amebiasis is a protozoal disease common for tropical countries. It is not frequently diagnosed in Central Russia, and is mainly seen in travelers, people with immunodeficiency, as well as in men who have sex with men. The main manifestation of the disease is intestinal damage with the development of diarrhea. With the hematogenic spread of the pathogen, extra-intestinal lesions of different organs may develop with the formation of abscesses in them. The liver, lungs, brain, and skin are most often involved in the inflammatory process. In this article, we describe a case of extrahepatic amebiasis with multiple liver abscesses, which presented difficulties in diagnosis. We provide details of observation and key laboratory findings as well as results of radiological examinations. Appearance of imported amebiasis in the Moscow region proves its actual importance and significance of timely diagnosis and etiotropic therapy. The aim of the article is to draw attention to the problem of diagnosis and prophylaxis of amebiasis in Central Russia as a result of migration and tourism to endemic territories.

About the authors

Olga A. Burgasova

Peoples’ Friendship University of Russia named after Patrice Lumumba

Email: oburgasova@mail.ru
ORCID iD: 0000-0002-5486-0837
SPIN-code: 5103-0451

MD, Dr. Sci. (Medicine), Professor

Russian Federation, 8 Mikluho-Maklaya street, 117198 Moscow

Sergei S. Lebedev

S.P. Botkin City Clinical Hospital; Russian Medical Academy of Continuous Professional Education

Email: lebedevssd@yandex.ru
ORCID iD: 0000-0001-5366-1281
SPIN-code: 2736-0683

MD, Cand. Sci. (Medicine), Assistant Professor

Russian Federation, 125284 Moscow; 125993 Moscow

Iuliia A. Klimova

Peoples’ Friendship University of Russia named after Patrice Lumumba

Author for correspondence.
Email: yua_klimova@rudn.ru
ORCID iD: 0000-0001-8936-721X
SPIN-code: 8821-5492

MD, Cand. Sci. (Medicine)

Russian Federation, 8 Mikluho-Maklaya street, 117198 Moscow

References

  1. Clinical recommendations (treatment protocol) for the provision of medical care to children with amebiasis. 2013. 66 p. Available from: http://niidi.ru/dotAsset/144a99cc-dcc1-443a-a862-d217a596d684.pdf (In Russ.)
  2. Tokmalaev A.K., Kozhevnikova G.M. Clinical parasitology: protozoa and helminthiasis. Textbook. Moscow: MIA; 2010. 432 p. (In Russ.)
  3. Shirley DT, Farr L, Watanabe K, Moonah S. A Review of the Global Burden, New Diagnostics, and Current Therapeutics for Amebiasis. Open Forum Infect Dis. 2018;5(7):ofy161. doi: 10.1093/ofid/ofy161
  4. Glutkina NV, Kulaga EYa, Zinchuk VV. Amebiasis: features of diagnosis in various forms of lesion (clinical case). Vestnik of Smolensk State Medical Academy. 2022;21(3):115–123. (In Russ.) doi: 10.37903/vsgma.2022.1.14
  5. Salles JM, Salles MJ, Moraes LA, Silva MC. Invasive amebiasis: an update on diagnosis and management. Expert Rev Anti Infect Ther. 2007;5(5):893–901. doi: 10.1586/14787210.5.5.893
  6. Billet AC, Salmon Rousseau A, Piroth L, Martins C. An underestimated sexually transmitted infection: amoebiasis. BMJ Case Rep. 2019;12(5):e228942. doi: 10.1136/bcr-2018-228942
  7. Knobloch J, Mannweiler E. Development and persistence of antibodies to Entamoeba histolytica in patients with amebic liver abscess. Analysis of 216 cases. Am J Trop Med Hyg. 1983;32(4): 727–732. doi: 10.4269/ajtmh.1983.32.727
  8. Dhariwal A, Youngs J, San Francisco A, Bicanic T. Late presentation of amoebic liver abscess. Lancet Infect Dis. 2020;20(2):259. doi: 10.1016/S1473-3099(19)30555-9 Erratum in: Lancet Infect Dis. 2020;20(4):e50. doi: 10.1016/S1473-3099(20)30127-4
  9. Akhmedova EF, Galyavin AV, Zotov AV. Challenging diagnosis of amebiasis in a non-endemic region: a clinical case. Almanac of Clinical Medicine. 2023;50(6):408–413. (In Russ.) doi: 10.18786/2072-0505-2022-50-026
  10. Yurchenko IN, Dyachkov VA, Fatenkov OV, et al. Clinical case of amoebic ulcerative colitis. Modern Problems of Science and Education. 2020;(6). (In Russ.) doi: 10.17513/spno.30376
  11. Pritt BS, Clark CG. Amebiasis. Mayo Clin Proc. 2008;83(10): 1154–1160. doi: 10.4065/83.10.1154
  12. Salata RA, Ravdin JI. The interaction of human neutrophils and Entamoeba histolytica increases cytopathogenicity for liver cell monolayers. J Infect Dis. 1986;154(1):19–26. doi: 10.1093/infdis/154.1.19
  13. Saidin S, Othman N, Noordin R. Update on laboratory diagnosis of amoebiasis. Eur J Clin Microbiol Infect Dis. 2019;38(1):15–38. doi: 10.1007/s10096-018-3379-3
  14. Kazymov BI, Svishcheva PO, Olkhovskaya MV, et al. Amoebic liver abscess: description of the clinical case. Bulletin of the Medical Institute “REAVIZ” (REHABILITATION, DOCTOR AND HEALTH). 2023;13(4):109–112. (In Russ.) doi: 10.20340/vmi-rvz.2023.4.CASE.1
  15. Ivanova MA, Karpov IA. Amebiasis. Educational and methodological guide. Minsk: BGMU; 2005. 19 p. (In Russ.)
  16. Ghosh JK, Goyal SK, Behera MK, et al. Efficacy of aspiration in amebic liver abscess. Trop Gastroenterol. 2015;36(4):251–255. doi: 10.7869/tg.299

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2. Fig. 1. Computed tomography of the abdominal cavity.

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3. Fig. 2. Computed tomography of the chest.

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