Severe course of leptospirosis: A case report
- Authors: Efremov D.O.1, Khuramshin A.R.1, Beloborodov V.B.2
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Affiliations:
- The National Medical Research Center of High Medical Technologies — the Central Military Clinical Hospital of A.A. Vishnevsky
- Russian Medical Academy of Continuous Professional Education
- Issue: Vol 29, No 2 (2024)
- Pages: 142-150
- Section: CASE REPORTS
- URL: https://journals.rcsi.science/1560-9529/article/view/257364
- DOI: https://doi.org/10.17816/EID627890
- ID: 257364
Cite item
Abstract
This study describes a clinical case of severe leptospirosis. Patient K., was admitted to the neurosurgical department on November 26, 2023, with a diagnosis of “Closed craniocerebral injury dated 22.11.2023. Severe brain injury. Linear fracture of the occipital bone. Eyelid hematoma. An abrasion of the upper eyelid on the right.” On November 29, 2023, an objective examination drew attention to an increase in body temperature to 39.5°C, subictericity of the sclera and skin, and conjunctival injections. Hemorrhagic rash appeared on the skin of the trunk and limbs. The hemodynamics was unstable, with episodes of arterial hypotension. Laboratory examination revealed mild anemia, signs of hepatic–renal insufficiency, hyperbilirubinemia, and increased concentrations of creatine phosphokinase, C-reactive protein, and procalcitonin. Fluctuations in hepatic–renal insufficiency and levels of creatine phosphokinase and procalcitonin increased. In addition, the differential diagnostic search aimed at identifying the following infectious diseases: hemorrhagic fever with renal syndrome, leptospirosis, malaria, and viral hepatitis. IgM to Leptospira interrogans were detected (December 11, 2023). The patient received antibacterial therapy, extracorporeal detoxification, artificial ventilation, infusion therapy, and correction of the hemostasis system. With the complex treatment, the patient’s condition stabilized, and the patient was discharged from the hospital on the 61st day with restoration of health.
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##article.viewOnOriginalSite##About the authors
Dmitriy O. Efremov
The National Medical Research Center of High Medical Technologies — the Central Military Clinical Hospital of A.A. Vishnevsky
Author for correspondence.
Email: Efremov-d24@mail.ru
ORCID iD: 0000-0001-7889-6052
SPIN-code: 7115-2713
MD, Cand. Sci. (Medicine)
Russian Federation, KrasnogorskAinur R. Khuramshin
The National Medical Research Center of High Medical Technologies — the Central Military Clinical Hospital of A.A. Vishnevsky
Email: ainur83@inbox.ru
ORCID iD: 0009-0006-7956-4694
SPIN-code: 6195-3308
Russian Federation, Krasnogorsk
Vladimir B. Beloborodov
Russian Medical Academy of Continuous Professional Education
Email: belvb1070@mail.ru
ORCID iD: 0000-0002-0544-4167
SPIN-code: 4233-2046
MD, Dr. Sci. (Medicine), Professor
Russian Federation, MoscowReferences
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