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Study of the lyophilic properties and cytotoxity of nanostructured bioceramics based on the ZrO2–Y2O3–СeO2 and ZrO2–Y2O3–Al2O3 systems


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Abstract

By the coprecipitation method, ceramic nanomaterials based on zirconia (t-ZrO2) with high tetragonality have been synthesized. The hydrophilic nature of the ceramic surface upon wetting with different liquids is established. By the method of culturing animal and human cells in vitro, it is revealed that the material shows no inhibitory effect on morphology and cell proliferation. The biocompatibility of the studied material based on t-ZrO2 with living cells has been proven, and prediction has been made to retain these properties during its implantation into the human body.

About the authors

M. Yu. Arsent’ev

Grebenshchikov Institute of Silicate Chemistry

Email: kovalko.n.yu@gmail.com
Russian Federation, St. Petersburg, 199155

K. A. Kolobov

Grebenshchikov Institute of Silicate Chemistry

Email: kovalko.n.yu@gmail.com
Russian Federation, St. Petersburg, 199155

O. A. Shilova

Grebenshchikov Institute of Silicate Chemistry; Ul’yanov (Lenin) St. Petersburg State Electrotechnical University (LETI)

Email: kovalko.n.yu@gmail.com
Russian Federation, St. Petersburg, 199155; St. Petersburg, 197376

N. Yu. Koval’ko

Grebenshchikov Institute of Silicate Chemistry

Author for correspondence.
Email: kovalko.n.yu@gmail.com
Russian Federation, St. Petersburg, 199155

M. V. Kalinina

Grebenshchikov Institute of Silicate Chemistry

Email: kovalko.n.yu@gmail.com
Russian Federation, St. Petersburg, 199155

L. V. Morozova

Grebenshchikov Institute of Silicate Chemistry

Email: kovalko.n.yu@gmail.com
Russian Federation, St. Petersburg, 199155

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