Pyrrolidine synthons for β-lactams

Z. R. Valiullina; A. N. Lobov; N. K. Selezneva; M. S. Miftakhov

doi:10.1134/S1070428016030106

Pyrrolidine synthons for β-lactams

作者: Valiullina Z.R.¹, Lobov A.N.¹, Selezneva N.K.¹, Miftakhov M.S.¹
隶属关系:
1. Ufa Institute of Organic Chemistry
期: 卷 52, 编号 3 (2016)
页面: 349-354
栏目: Article
URL: https://journals.rcsi.science/1070-4280/article/view/213866
DOI: https://doi.org/10.1134/S1070428016030106
ID: 213866

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详细

Fused tricyclic aziridines, methyl rel-(2R,2aR,3R,4R,4aR,4bS)- and rel-(2S,2aR,3R,4R,4aR,4bS)-4-hydroxy-2,4a-dimethoxyhexahydro-1-oxa-2b-azacyclopropa[cd]pentalene-3-carboxylates, have been synthesized as possible precursors to β-lactams. The product structure has been determined by two-dimensional NMR techniques in combination with computational methods.