Synthesis of methyl 4-aryl-2-{[4-(carbamimidoylsulfamoyl)- phenyl]amino}-4-oxobut-2-enoates

V. L. Gein; O. V. Bobrovskaya; I. V. Kovtonogova; V. D. Belonogova; Yu. L. Danilov; O. E. Nasakin; M. I. Kazantseva

doi:10.1134/S1070428016120083

Synthesis of methyl 4-aryl-2-{[4-(carbamimidoylsulfamoyl)- phenyl]amino}-4-oxobut-2-enoates

Autores: Gein V.L.¹, Bobrovskaya O.V.¹, Kovtonogova I.V.¹, Belonogova V.D.¹, Danilov Y.L.², Nasakin O.E.³, Kazantseva M.I.³
Afiliações:
1. Perm State Pharmaceutical Academy
2. Perm Military Institute of Interior Ministry Troops
3. I.N. Ul’yanov Chuvash State University
Edição: Volume 52, Nº 12 (2016)
Páginas: 1762-1764
Seção: Article
URL: https://journals.rcsi.science/1070-4280/article/view/215419
DOI: https://doi.org/10.1134/S1070428016120083
ID: 215419

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Resumo

Methyl aroylpyruvates reacted with 4-amino-N-carbamimidoylbenzene-1-sulfonamide in acetic acid–ethanol (1: 1) to give methyl 4-aryl-2-{[4-(carbamimidoylsulfamoyl)phenyl]amino}-4-oxobut-2-enoates which were found to exist in solution as mixtures of Z and E isomers.