Hydrolytic Degradation of Some Fused and Spiro Compounds Containing a System of 2-Amino-3-Cyano-4H-Pyran

Abstract

Heating some derivatives of 5,6,7,8-tetrahydro-4Н-chromene and 1,2,5′,6′,7′,8′-hexahydrospiro-[indole-3,4′-chromene] in acid environment causes a hydrolytic degradation with the formation of functionally substituted carboxylic acids. A derivative of 1,2-dihydrospiro[indole-3,4′-pyran] in the same conditions afforded a mixture of products resulting from retro-Michael decomposition and recyclization.