Green Nano-Silica Sulfuric Acid-Catalyzed Synthesis of New 6-Amino-8-aryl-7-(benzenesulfonyl)-2-(hydroxymethyl)-pyrano[3,2-b]pyran-4(8H)-one Derivatives

Abstract

Some new 6-amino-8-aryl-7-(benzenesulfonyl)-2-(hydroxymethyl)pyrano[3,2-b]pyran-4(8H)-ones have been synthesized in improved yields by one-pot three-component reaction of aromatic aldehydes with benzenesulfonylacetonitrile and 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one in the presence of nano-silica sulfuric acid. The catalyst can be recovered by simple filtration and reused further.