Condensation of 5-Acetyl-3,4-dihydropyrimidin-2(1 H )-ones with Hydrazine

O. I. Kharaneko; T. M. Pekhtereva; A. O. Kharaneko

doi:10.1134/S1070428019110058

Condensation of 5-Acetyl-3,4-dihydropyrimidin-2(1H)-ones with Hydrazine

作者: Kharaneko O.I.¹, Pekhtereva T.M.¹, Kharaneko A.O.¹
隶属关系:
1. Litvinenko Institute of Physical Organic and Coal Chemistry
期: 卷 55, 编号 11 (2019)
页面: 1674-1678
栏目: Article
URL: https://journals.rcsi.science/1070-4280/article/view/221343
DOI: https://doi.org/10.1134/S1070428019110058
ID: 221343

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详细

3,4-Dihydropyrimidines obtained by the Biginelli reaction react with hydrazine to give a mixture of N-[(3,5-dimethyl-1H-pyrazol-4-yl)(R)methyl]ureas and 4-R-3,7a-dimethyl-1,3a,4,5,7,7a-hexahydro-6H-pyrazolo[3,4-d]pyrimidin-6-ones. The latter transform into N-[(3,5-dimethyl-1H-pyrazol-4-yl)(R)methyl]ureas in an acidic medium.