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New Synthesis of Functionalized Nicotinamides


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Resumo

An efficient method has been developed for the synthesis of 6-(alkylsulfanyl)-4-aryl(hetaryl)-N-aryl-5-cyano-2-methylpyridine-3-carboxamides by condensation of aromatic or heteroaromatic aldehydes with cyanothioacetamide and acetoacetanilides in the presence of triethylamine or morpholine, followed by S-alkylation.

Sobre autores

V. Khrustalev

“Kurchatov Institute” National Research Center; Peoples’ Friendship University of Russia

Email: nenajdenko@gmail.com
Rússia, Moscow; Moscow

V. Nenajdenko

Faculty of Chemistry

Autor responsável pela correspondência
Email: nenajdenko@gmail.com
Rússia, Moscow

I. Dyachenko

Taras Shevchenko Lugansk National University

Email: nenajdenko@gmail.com
Ucrânia, Lugansk

I. Kalashnik

Taras Shevchenko Lugansk National University

Email: nenajdenko@gmail.com
Ucrânia, Lugansk

V. Dyachenko

Taras Shevchenko Lugansk National University

Email: nenajdenko@gmail.com
Ucrânia, Lugansk

P. Dorovatovskii

“Kurchatov Institute” National Research Center

Email: nenajdenko@gmail.com
Rússia, Moscow

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Declaração de direitos autorais © Pleiades Publishing, Ltd., 2019