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Undec-10-enoic Acid in the Synthesis of Macroheterocycles Containing Hydrazide and Ester Fragments


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Abstract

Four potentially biologically active 31-, 32-, and 33-membered macroheterocycles with ester and hydrazide fragments have been synthesized by [1 + 1]-condensation of ethane-1,2-diyl bis(10-oxoundecanoate) with malonic, glutaric, L-(+)-tartaric, and pyridine-2,6-dicarboxylic acid dihydrazides. The product structure has been confirmed by IR, NMR, and mass spectra.

About the authors

G. R. Mingaleeva

Ufa Institute of Chemistry, Ufa Research Center

Email: insect@anrb.ru
Russian Federation, Ufa, Bashkortostan

M. P. Yakovleva

Ufa Institute of Chemistry, Ufa Research Center

Email: insect@anrb.ru
Russian Federation, Ufa, Bashkortostan

R. R. Salakhutdinov

Ufa Institute of Chemistry, Ufa Research Center

Email: insect@anrb.ru
Russian Federation, Ufa, Bashkortostan

A. G. Tolstikov

Ufa Institute of Chemistry, Ufa Research Center

Email: insect@anrb.ru
Russian Federation, Ufa, Bashkortostan

G. Yu. Ishmuratov

Ufa Institute of Chemistry, Ufa Research Center

Author for correspondence.
Email: insect@anrb.ru
Russian Federation, Ufa, Bashkortostan

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