Synthesis of Ethyl 5-(Arylcarbamoyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylates

S. S. Hayotsyan; A. A. Sargsyan; S. G. Konkova; A. Kh. Khachatryan; A. E. Badasyan; K. A. Avagyan; H. A. Panosyan; A. G. Ayvazyan; M. S. Sargsyan

doi:10.1134/S1070428019040080

Synthesis of Ethyl 5-(Arylcarbamoyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylates

Authors: Hayotsyan S.S.¹, Sargsyan A.A.¹, Konkova S.G.¹, Khachatryan A.K.¹^,2, Badasyan A.E.¹, Avagyan K.A.¹, Panosyan H.A.¹, Ayvazyan A.G.¹, Sargsyan M.S.¹
Affiliations:
1. Scientific Technological Center of Organic and Pharmaceutical Chemistry
2. State Academy of Crisis Management
Issue: Vol 55, No 4 (2019)
Pages: 469-472
Section: Article
URL: https://journals.rcsi.science/1070-4280/article/view/220255
DOI: https://doi.org/10.1134/S1070428019040080
ID: 220255

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Abstract

A one-step procedure has been developed for the synthesis of previously unknown ethyl 5-(arylcarbamoyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylates by reaction of ethyl 2-cyano-3-ethoxyprop-2-enoate with acetoacetanilides in the presence of a catalytic amount of piperidine in ethanol at room temperature.