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Synthesis of 2-Alkylsulfanyl-6-amino-4-aryl-5-cyanonicotinonitriles by Recyclization of 2,6-Diamino-4-aryl-3,5-dicyano-4Н-thiopyrans with Alkyl Halides


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Abstract

2,6-Diamino-4-aryl-3,5-dicyano-4Н-thiopyrans in DMF in the presence of bases recycle into pyridine derivatives. After adding of haloalkanes diverse 2-(alkylsulfanyl)-6-amino-4-aryl-5-cyano-nicotinonitriles are formed.

About the authors

I. V. Dyachenko

Taras Shevchenko Lugansk State University

Email: nenajdenko@gmail.com
Ukraine, ul. Oboronnaya 2, Lugansk, 95006

V. D. Dyachenko

Taras Shevchenko Lugansk State University

Email: nenajdenko@gmail.com
Ukraine, ul. Oboronnaya 2, Lugansk, 95006

P. V. Dorovatovskii

National Research Center “Kurchatov Institute”

Email: nenajdenko@gmail.com
Russian Federation, pl. Akademika Kurchatova 1, Moscow, 123182

V. N. Khrustalev

National Research Center “Kurchatov Institute”; Peoples’ Friendship University of Russia

Email: nenajdenko@gmail.com
Russian Federation, pl. Akademika Kurchatova 1, Moscow, 123182; ul. Miklukho-Maklaya 6, Moscow, 117198

V. G. Nenaydenko

Moscow State University

Author for correspondence.
Email: nenajdenko@gmail.com
Russian Federation, Leninskie gory 1, Moscow, 119991

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