Email this article One-Pot Synthesis of 3,5-Disubstituted 1,2,4-Oxadiazoles Using Catalytic System NaOH‒DMSO
- Authors: Pankrat’eva V.E.1, Sharonova T.V.1, Tarasenko M.V.2, Baikov S.V.3, Kofanov E.R.2
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Affiliations:
- Transfer Center of Pharmaceutical Technology
- Yaroslavl State Technical University
- St. Petersburg State University
- Issue: Vol 54, No 8 (2018)
- Pages: 1250-1255
- Section: Article
- URL: https://journals.rcsi.science/1070-4280/article/view/218760
- DOI: https://doi.org/10.1134/S1070428018080213
- ID: 218760
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Abstract
One-pot convenient process was developed for the production of 3,5-disubstituted 1,2,4-oxadiazoles by reaction of amidoximes with anhydrides or acyl chlorides in a system NaOH‒DMSO. The reaction proceeds at room temperature with high yields.
About the authors
V. E. Pankrat’eva
Transfer Center of Pharmaceutical Technology
Email: mkarunnaya@mail.ru
Russian Federation, Yaroslavl, 150000
T. V. Sharonova
Transfer Center of Pharmaceutical Technology
Email: mkarunnaya@mail.ru
Russian Federation, Yaroslavl, 150000
M. V. Tarasenko
Yaroslavl State Technical University
Author for correspondence.
Email: mkarunnaya@mail.ru
Russian Federation, Moskovskii pr. 88, Yaroslavl, 150023
S. V. Baikov
St. Petersburg State University
Email: mkarunnaya@mail.ru
Russian Federation, St. Petersburg, 199034
E. R. Kofanov
Yaroslavl State Technical University
Email: mkarunnaya@mail.ru
Russian Federation, Moskovskii pr. 88, Yaroslavl, 150023
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