Email this article Synthesis of Dicarboxylic Acid Amides and Diamides on the Basis of [4-(4-Methoxyphenyl)tetrahydro-2H-pyran-4-yl]methanamine
- Authors: Aghekyan A.A.1, Mkryan G.G.1, Muradyan R.E.1, Tumajyan A.E.1
-
Affiliations:
- Mndzhoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry
- Issue: Vol 54, No 6 (2018)
- Pages: 886-891
- Section: Article
- URL: https://journals.rcsi.science/1070-4280/article/view/218088
- DOI: https://doi.org/10.1134/S1070428018060106
- ID: 218088
Cite item
Open Access
Access granted
Subscription Access
Abstract
The condensation of various nonaromatic amines with ethyl N-{[4-(4-methoxyphenyl)tetrahydro-2H-pyran-4-yl]methyl}oxamate prepared from [4-(4-methoxyphenyl)tetrahydro-2H-pyran-4-yl]methanamine and diethyl oxalate afforded the corresponding N,N'-disubstituted oxamides. N-Aryloxamides were synthesized by the reaction of [4-(4-methoxyphenyl)tetrahydro-2H-pyran-4-yl]methanamine with ethyl N-aryloxamates. The condensation of N-{[4-(4-methoxyphenyl)tetrahydro-2H-pyran-4-yl]methyl}succinamic acid with primary amines gave N,N'-disubstituted siccinamides.
About the authors
A. A. Aghekyan
Mndzhoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry
Author for correspondence.
Email: aaghekyan@mail.ru
Armenia, pr. Azatutyan 26, Yerevan, 0014
G. G. Mkryan
Mndzhoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry
Email: aaghekyan@mail.ru
Armenia, pr. Azatutyan 26, Yerevan, 0014
R. E. Muradyan
Mndzhoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry
Email: aaghekyan@mail.ru
Armenia, pr. Azatutyan 26, Yerevan, 0014
A. E. Tumajyan
Mndzhoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry
Email: aaghekyan@mail.ru
Armenia, pr. Azatutyan 26, Yerevan, 0014
Supplementary files
