Synthesis and Structure of New Substituted Pyrimidinone with Unsaturated Side Chain
- Authors: Harutyunyan A.A.1,2, Gukasyan G.T.1, Panosyan H.A.2, Tamazyan R.A.2, Aivazyan A.G.2, Danagulyan G.G.1,2
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Affiliations:
- Russian–Armenian (Slavic) University
- The Scientifical and Technological Centre of Organic and Pharmaceutical Chemistry
- Issue: Vol 54, No 5 (2018)
- Pages: 771-775
- Section: Article
- URL: https://journals.rcsi.science/1070-4280/article/view/217891
- DOI: https://doi.org/10.1134/S1070428018050160
- ID: 217891
Cite item
Abstract
Melting of a mixture of 5-substituted 2,4-dimethyl-1,6-dihydropyrimidin-6-ones with cinnamic aldehyde, 1-methylindoline-2,3-dione and 6-methoxy-2-chloroquinoline-3-carbaldehyde in the presence of ZnCl2 led to the formation of substituted pyrimidines with conjugated bonds in the position 2. The structure of synthesized compounds as 2-isomers was confirmed by 2D 1H NMR NOESY data.
About the authors
A. A. Harutyunyan
Russian–Armenian (Slavic) University; The Scientifical and Technological Centre of Organic and Pharmaceutical Chemistry
Author for correspondence.
Email: harutyunyan.arthur@yahoo.com
Armenia, Yerevan, 0051; Azatutyan pr. 26, Yerevan, 0014
G. T. Gukasyan
Russian–Armenian (Slavic) University
Email: harutyunyan.arthur@yahoo.com
Armenia, Yerevan, 0051
H. A. Panosyan
The Scientifical and Technological Centre of Organic and Pharmaceutical Chemistry
Email: harutyunyan.arthur@yahoo.com
Armenia, Azatutyan pr. 26, Yerevan, 0014
R. A. Tamazyan
The Scientifical and Technological Centre of Organic and Pharmaceutical Chemistry
Email: harutyunyan.arthur@yahoo.com
Armenia, Azatutyan pr. 26, Yerevan, 0014
A. G. Aivazyan
The Scientifical and Technological Centre of Organic and Pharmaceutical Chemistry
Email: harutyunyan.arthur@yahoo.com
Armenia, Azatutyan pr. 26, Yerevan, 0014
G. G. Danagulyan
Russian–Armenian (Slavic) University; The Scientifical and Technological Centre of Organic and Pharmaceutical Chemistry
Email: harutyunyan.arthur@yahoo.com
Armenia, Yerevan, 0051; Azatutyan pr. 26, Yerevan, 0014
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