Email this article Synthesis of (2R,4R)-2-alkyl-3-(2-mercaptobenzoyl)thiazolidine-4-carboxylic acids
- Authors: Ershov А.Y.1, Lagoda I.V.2, Nasledov D.G.1, Vasil’eva M.Y.1, Kuleshova L.Y.3, Pavlova L.V.2, Yakimanskii A.V.1,4
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Affiliations:
- Institute of Macromolecular Compounds
- R&D Test Center (of Medico-Biological Protection), State R&D Institute of Military Medicine
- Ryazan Medical University
- St. Petersburg State University
- Issue: Vol 53, No 11 (2017)
- Pages: 1682-1686
- Section: Article
- URL: https://journals.rcsi.science/1070-4280/article/view/216937
- DOI: https://doi.org/10.1134/S1070428017110124
- ID: 216937
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Abstract
Basing on natural amino acid L-cysteine, commercially available aliphatic aldehydes, 2-acetylsulfanylbenzoyl chloride and 2,2′-disulfandiyldibenzoyl dichloride a synthesis was developed of (2R,4R)-2-alkyl-3-(2-mercaptobenzoyl)thiazolidine-4-carboxylic acids, potential antihypertensive compounds, inhibitors of angiotensin transforming enzyme.
About the authors
А. Yu. Ershov
Institute of Macromolecular Compounds
Author for correspondence.
Email: ershov305@mail.ru
Russian Federation, V.O., Bol’shoi pr. 31, St. Petersburg, 199004
I. V. Lagoda
R&D Test Center (of Medico-Biological Protection), State R&D Institute of Military Medicine
Email: ershov305@mail.ru
Russian Federation, St. Petersburg
D. G. Nasledov
Institute of Macromolecular Compounds
Email: ershov305@mail.ru
Russian Federation, V.O., Bol’shoi pr. 31, St. Petersburg, 199004
M. Yu. Vasil’eva
Institute of Macromolecular Compounds
Email: ershov305@mail.ru
Russian Federation, V.O., Bol’shoi pr. 31, St. Petersburg, 199004
L. Yu. Kuleshova
Ryazan Medical University
Email: ershov305@mail.ru
Russian Federation, Ryazan
L. V. Pavlova
R&D Test Center (of Medico-Biological Protection), State R&D Institute of Military Medicine
Email: ershov305@mail.ru
Russian Federation, St. Petersburg
A. V. Yakimanskii
Institute of Macromolecular Compounds; St. Petersburg State University
Email: ershov305@mail.ru
Russian Federation, V.O., Bol’shoi pr. 31, St. Petersburg, 199004; St. Petersburg
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