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Synthesis of phenyl analog of retinoic acid methyl ester proceeding from 3-(bromomethyl)but-3-enal diethylacetal


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Abstract

Aromatic analog of retinoic acid methyl ester was prepared using a convenient prenylating agent, 3-(bromomethyl)but-3-enal diethylacetal, and Barbier reaction in the key stage of building up the carbon chain of target molecules. A version is offered of the synthesis of methylidene analog of aromatic retinoic acid.

About the authors

V. S. Masyuk

Belarus State University

Email: i.mineyeva@yandex.ru
Belarus, pr. Nezavisimosti 4, Minsk, 220030

I. V. Mineeva

Belarus State University

Author for correspondence.
Email: i.mineyeva@yandex.ru
Belarus, pr. Nezavisimosti 4, Minsk, 220030

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