Email this article Synthesis of 5-aryl(hetaryl)-4-methyl-2-(furan-2-yl)-1H-imidazol-1-oles
- Authors: Os’kina I.A.1, Tikhonov А.Y.1
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Affiliations:
- Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch
- Issue: Vol 53, No 8 (2017)
- Pages: 1239-1242
- Section: Article
- URL: https://journals.rcsi.science/1070-4280/article/view/216727
- DOI: https://doi.org/10.1134/S1070428017080139
- ID: 216727
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Abstract
Reaction of 2-(hydroxyamino)-1-R-propan-1-one oximes with furfural in methanol afforded the corresponding α-furylnitrones. The cyclization of α-furylnitrones in alkaline medium results in the formation of 5-aryl(hetaryl)-2-(furan-2-yl)-1H-imidazol-1-oles.
About the authors
I. A. Os’kina
Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch
Author for correspondence.
Email: oi@nioch.nsc.ru
Russian Federation, pr. Akademika Lavryent’eva 9, Novosibirsk, 630090
А. Ya. Tikhonov
Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch
Email: oi@nioch.nsc.ru
Russian Federation, pr. Akademika Lavryent’eva 9, Novosibirsk, 630090
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