Potential synthetic adaptogens: IV. Synthesis and study of basicity of new  N -[(adamantan-1-yl)methyl]aniline derivatives

I. A. Novakov; A. S. Babushkin; A. A. Vernigora; A. S. Mkrtchyan; M. B. Navrotskii; B. S. Orlinson; S. N. Voloboev

doi:10.1134/S1070428017050049

Potential synthetic adaptogens: IV. Synthesis and study of basicity of new N-[(adamantan-1-yl)methyl]aniline derivatives

Authors: Novakov I.A.¹, Babushkin A.S.¹, Vernigora A.A.¹, Mkrtchyan A.S.¹, Navrotskii M.B.¹, Orlinson B.S.¹, Voloboev S.N.²
Affiliations:
1. Volgograd State Technical University
2. Open Joint Stocks Co “LUKOIL-Volgogradneftepererabotka,”
Issue: Vol 53, No 5 (2017)
Pages: 663-672
Section: Article
URL: https://journals.rcsi.science/1070-4280/article/view/216174
DOI: https://doi.org/10.1134/S1070428017050049
ID: 216174

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Abstract

Aiming at purposeful designing new conformationally labile bromantane analogs we performed experimental and theoretical evaluation of the basicity of new and formerly prepared compounds of this series. The connection was established between the chemical structure and the basicity of compounds obtained and preferred structures were determined for subsequent biological investigations.