Synthesis of new 1-(3,4-dimethylphenyl)-1,5-dihydropyrazolo[3,4-d]pyrimidin-4-one derivatives
- Авторы: Zhidkov M.E.1, Kutkin A.V.1, Fetisova E.N.1, Zverev D.M.1, Zaraeva N.V.1, Gorokhov V.V.1, Chubarova O.V.1
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Учреждения:
- State Research Institute of Organic Chemistry and Technology
- Выпуск: Том 53, № 4 (2017)
- Страницы: 592-598
- Раздел: Review
- URL: https://journals.rcsi.science/1070-4280/article/view/216094
- DOI: https://doi.org/10.1134/S1070428017040157
- ID: 216094
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Аннотация
New substituted pyrazolo[3,4-d]pyrimidin-4-ones have been synthesized as a result of a series of transformations including hydrolysis of ethyl 5-amino-1H-pyrazole-4-carboxylates, cyclization of the carboxylic acids thus obtained to pyrazolo[3,4-d][1,3]oxazin-4(1H)-ones, and treatment of the latter with substituted anilines. The final pyrazolo[3,4-d]pyrimidin-4-one derivatives can also be synthesized from 5-(arylamido)-1H-pyrazole-4-carboxylic acids in the presence of a catalytic amount of anhydrous zinc(II) chloride.
Об авторах
M. Zhidkov
State Research Institute of Organic Chemistry and Technology
Email: dir@gosniiokht.ru
Россия, sh. Entuziastov 23, Moscow, 111024
A. Kutkin
State Research Institute of Organic Chemistry and Technology
Email: dir@gosniiokht.ru
Россия, sh. Entuziastov 23, Moscow, 111024
E. Fetisova
State Research Institute of Organic Chemistry and Technology
Автор, ответственный за переписку.
Email: dir@gosniiokht.ru
Россия, sh. Entuziastov 23, Moscow, 111024
D. Zverev
State Research Institute of Organic Chemistry and Technology
Email: dir@gosniiokht.ru
Россия, sh. Entuziastov 23, Moscow, 111024
N. Zaraeva
State Research Institute of Organic Chemistry and Technology
Email: dir@gosniiokht.ru
Россия, sh. Entuziastov 23, Moscow, 111024
V. Gorokhov
State Research Institute of Organic Chemistry and Technology
Email: dir@gosniiokht.ru
Россия, sh. Entuziastov 23, Moscow, 111024
O. Chubarova
State Research Institute of Organic Chemistry and Technology
Email: dir@gosniiokht.ru
Россия, sh. Entuziastov 23, Moscow, 111024
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