Email this article Synthesis and some transformations of 3-(2,2-dimethyloxan-4-yl)-4-methylpentanenitrile
- Authors: Harutyunyan N.S.1,2, Nazaryan R.L.1,2, Hakobyan L.A.1,2, Panosyan H.A.3,2, Gevorgyan G.A.1,2
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Affiliations:
- Mndzhoyan Institute of Fine Organic Chemistry
- Scientific Technological Center of Organic and Pharmaceutical Chemistry
- Molecular Structure Research Center
- Issue: Vol 53, No 1 (2017)
- Pages: 57-61
- Section: Article
- URL: https://journals.rcsi.science/1070-4280/article/view/215616
- DOI: https://doi.org/10.1134/S1070428017010109
- ID: 215616
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Abstract
2,2-Dimethyloxane-4-carbaldehyde reacted with ethyl cyanoacetate to give ethyl 2-cyano-3-(2,2-dimethyloxan-4-yl)prop-2-enoate whose reaction with isopropylmagnesium bromide afforded ethyl 2-cyano-3-(2,2-dimethyloxan-4-yl)-4-methylpentanoate. Elimination of the ester group from the latter led to the formation of 3-(2,2-dimethyloxan-4-yl)-4-methylpentanenitrile.
About the authors
N. S. Harutyunyan
Mndzhoyan Institute of Fine Organic Chemistry; Scientific Technological Center of Organic and Pharmaceutical Chemistry
Email: gyulgev@gmail.com
Armenia, Yerevan; pr. Azatutyan 26, Yerevan, 0014
R. L. Nazaryan
Mndzhoyan Institute of Fine Organic Chemistry; Scientific Technological Center of Organic and Pharmaceutical Chemistry
Email: gyulgev@gmail.com
Armenia, Yerevan; pr. Azatutyan 26, Yerevan, 0014
L. A. Hakobyan
Mndzhoyan Institute of Fine Organic Chemistry; Scientific Technological Center of Organic and Pharmaceutical Chemistry
Email: gyulgev@gmail.com
Armenia, Yerevan; pr. Azatutyan 26, Yerevan, 0014
H. A. Panosyan
Molecular Structure Research Center; Scientific Technological Center of Organic and Pharmaceutical Chemistry
Email: gyulgev@gmail.com
Armenia, Yerevan; pr. Azatutyan 26, Yerevan, 0014
G. A. Gevorgyan
Mndzhoyan Institute of Fine Organic Chemistry; Scientific Technological Center of Organic and Pharmaceutical Chemistry
Author for correspondence.
Email: gyulgev@gmail.com
Armenia, Yerevan; pr. Azatutyan 26, Yerevan, 0014
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