Synthesis and some transformations of 3-(2,2-dimethyloxan-4-yl)-4-methylpentanenitrile


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2,2-Dimethyloxane-4-carbaldehyde reacted with ethyl cyanoacetate to give ethyl 2-cyano-3-(2,2-dimethyloxan-4-yl)prop-2-enoate whose reaction with isopropylmagnesium bromide afforded ethyl 2-cyano-3-(2,2-dimethyloxan-4-yl)-4-methylpentanoate. Elimination of the ester group from the latter led to the formation of 3-(2,2-dimethyloxan-4-yl)-4-methylpentanenitrile.

作者简介

N. Harutyunyan

Mndzhoyan Institute of Fine Organic Chemistry; Scientific Technological Center of Organic and Pharmaceutical Chemistry

Email: gyulgev@gmail.com
亚美尼亚, Yerevan; pr. Azatutyan 26, Yerevan, 0014

R. Nazaryan

Mndzhoyan Institute of Fine Organic Chemistry; Scientific Technological Center of Organic and Pharmaceutical Chemistry

Email: gyulgev@gmail.com
亚美尼亚, Yerevan; pr. Azatutyan 26, Yerevan, 0014

L. Hakobyan

Mndzhoyan Institute of Fine Organic Chemistry; Scientific Technological Center of Organic and Pharmaceutical Chemistry

Email: gyulgev@gmail.com
亚美尼亚, Yerevan; pr. Azatutyan 26, Yerevan, 0014

H. Panosyan

Molecular Structure Research Center; Scientific Technological Center of Organic and Pharmaceutical Chemistry

Email: gyulgev@gmail.com
亚美尼亚, Yerevan; pr. Azatutyan 26, Yerevan, 0014

G. Gevorgyan

Mndzhoyan Institute of Fine Organic Chemistry; Scientific Technological Center of Organic and Pharmaceutical Chemistry

编辑信件的主要联系方式.
Email: gyulgev@gmail.com
亚美尼亚, Yerevan; pr. Azatutyan 26, Yerevan, 0014

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