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Chemical transformations of tetracyclo[3.3.1.13,7.01,3]decane (1,3-dehydroadamantane): II. Reaction of 1,3-dehydroadamantane with N,N-dialkylcarboxamides


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Abstract

Alkylation of N,N-dialkylcarboxamides with 1,3-dehydroadamantane has been accomplished for the first time. The reaction involves the C–H bond in the α-position with respect to the carbonyl group and provides a convenient one-step preparation of substituted carboxylic acid amides containing an 1-adamantyl substituent and a pharmacophoric group in the amide moiety.

About the authors

V. M. Mokhov

Volgograd State Technical University

Email: butov@volpi.ru
Russian Federation, pr. Lenina 28, Volgograd, 400005

G. M. Butov

Volzhskii Polytechnic Institute (Branch)

Author for correspondence.
Email: butov@volpi.ru
Russian Federation, ul. Engel’sa 42a, Volzhskii, Volgograd oblast, 404121

K. R. Saad

Volzhskii Polytechnic Institute (Branch)

Email: butov@volpi.ru
Russian Federation, ul. Engel’sa 42a, Volzhskii, Volgograd oblast, 404121

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