Hydrazides of 4-aryl(hetaryl)-2-oxopyrrolidine-3-carboxylic acids: Synthesis and structure

N. V. Gorodnicheva; E. S. Ostroglyadov; O. S. Vasil’eva; V. V. Pelipko; V. V. Gurzhii; V. M. Berestovitskaya; E. S. Lipina

doi:10.1134/S1070428016110129

Hydrazides of 4-aryl(hetaryl)-2-oxopyrrolidine-3-carboxylic acids: Synthesis and structure

Authors: Gorodnicheva N.V.¹, Ostroglyadov E.S.¹, Vasil’eva O.S.¹, Pelipko V.V.¹, Gurzhii V.V.², Berestovitskaya V.M.¹, Lipina E.S.¹
Affiliations:
1. Herzen Russian State Pedagogical University
2. St. Petersburg State University
Issue: Vol 52, No 11 (2016)
Pages: 1616-1624
Section: Article
URL: https://journals.rcsi.science/1070-4280/article/view/215231
DOI: https://doi.org/10.1134/S1070428016110129
ID: 215231

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Abstract

Proceeding from reactions of methyl 4-aryl(hetaryl)-2-oxopyrrolidine-3-caroxylates with hydrazine and phenylhydrazine a series of hydrazides of the corresponding 2-oxopyrrolidine-3-carboxylic acids was obtained combining in the molecule a lactam ring and carbohydrazide groups. Phenylhydrazides of 2-oxopyrrolidine-3-carboxylic acids possess the Z-configuration.