Email this article Domino reactions of pyrazol-5-amines with arylglyoxals and malononitrile
- Authors: Petrova O.N.1, Lipson V.V.1,2,3, Zamigajlo L.L.1, Shirobokova M.G.1, Musatov V.I.1, Dmitrienko D.A.3
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Affiliations:
- Research and Development Complex “Institute of Single Crystals”
- Danilevskii Institute of the Endocrinal Pathology Problems
- Karazin Kharkiv National University
- Issue: Vol 52, No 8 (2016)
- Pages: 1168-1172
- Section: Article
- URL: https://journals.rcsi.science/1070-4280/article/view/214831
- DOI: https://doi.org/10.1134/S1070428016080121
- ID: 214831
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Abstract
Domino reactions of 3-methylpyrazol-5-amine and 1-phenyl-3-methylpyrazol-5-amine with arylglyoxal hydrates and malononitrile in alcohol proceed regioselectively and lead to the formation of 6-aminopyrazolo[3,4-b]pyridine-5-carbonitrile.
About the authors
O. N. Petrova
Research and Development Complex “Institute of Single Crystals”
Email: lipson@ukr.net
Ukraine, Kharkiv
V. V. Lipson
Research and Development Complex “Institute of Single Crystals”; Danilevskii Institute of the Endocrinal Pathology Problems; Karazin Kharkiv National University
Author for correspondence.
Email: lipson@ukr.net
Ukraine, Kharkiv; ul. Alchevskikh 10, Kharkiv, 61002; Kharkiv
L. L. Zamigajlo
Research and Development Complex “Institute of Single Crystals”
Email: lipson@ukr.net
Ukraine, Kharkiv
M. G. Shirobokova
Research and Development Complex “Institute of Single Crystals”
Email: lipson@ukr.net
Ukraine, Kharkiv
V. I. Musatov
Research and Development Complex “Institute of Single Crystals”
Email: lipson@ukr.net
Ukraine, Kharkiv
D. A. Dmitrienko
Karazin Kharkiv National University
Email: lipson@ukr.net
Ukraine, Kharkiv
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