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Synthesis of a chiral building block for the C6‒C9 fragment of epothilones


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Abstract

A procedure has been developed for the synthesis of a new chiral building block for epothilone analogs starting from L-malic acid.

About the authors

R. F. Valeev

Institute of Chemistry, Ufa Research Center

Email: bioreg@anrb.ru
Russian Federation, pr. Oktyabrya 71, Ufa, Bashkortostan, 450054

A. M. Davletbaev

Bashkir State University

Email: bioreg@anrb.ru
Russian Federation, ul. Zaki Validi 32, Ufa, Bashkortostan, 450074

R. F. Talipov

Bashkir State University

Email: bioreg@anrb.ru
Russian Federation, ul. Zaki Validi 32, Ufa, Bashkortostan, 450074

M. S. Miftakhov

Institute of Chemistry, Ufa Research Center

Author for correspondence.
Email: bioreg@anrb.ru
Russian Federation, pr. Oktyabrya 71, Ufa, Bashkortostan, 450054

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