Email this article First catalyst- and solvent-free synthesis of 3,4-dihydropyrimidin-2(1H)-ones and -thiones
- Authors: Hajjami M.1, Ghiasbeygi E.1
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Affiliations:
- Department of Chemistry, Faculty of Science
- Issue: Vol 52, No 3 (2016)
- Pages: 429-432
- Section: Article
- URL: https://journals.rcsi.science/1070-4280/article/view/213983
- DOI: https://doi.org/10.1134/S1070428016030222
- ID: 213983
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Abstract
A completely green and environmentally benign Biginelli synthesis of 3,4-dihydropyrimidine-2(1H)-ones and -thiones by one-pot three-component reaction of aromatic aldehydes with ethyl acetoacetate and urea or thiourea without any catalyst under solvent-free conditions is described.
About the authors
M. Hajjami
Department of Chemistry, Faculty of Science
Author for correspondence.
Email: mhajjami@yahoo.com
Iran, Islamic Republic of, Ilam
E. Ghiasbeygi
Department of Chemistry, Faculty of Science
Email: mhajjami@yahoo.com
Iran, Islamic Republic of, Ilam
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