Email this article N-(4-methoxy-3-nitrobenzyl) derivatives of some nitrogen-containing heterocycles
- Authors: Harutyunyan A.A.1
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Affiliations:
- Mndzhoyan Institute of Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry
- Issue: Vol 52, No 1 (2016)
- Pages: 76-79
- Section: Article
- URL: https://journals.rcsi.science/1070-4280/article/view/213512
- DOI: https://doi.org/10.1134/S1070428016010140
- ID: 213512
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Abstract
A number of nitrogen heterocycles reacted with 4-methoxy-3-nitrobenzyl chloride in dimethyl-formamide in the presence of potassium carbonate to give the corresponding N-(4-methoxy-3-nitrobenzyl) derivatives. The reaction of 5-fluoro-1,3-bis(4-methoxy-3-nitrobenzyl)pyrimidine-2,4(1H,3H)-dione with aqueous methylamine afforded N,N′-bis(4-methylamino-3-nitrobenzyl)urea, whereas analogous reaction with 1-(4-methoxy-3-nitrobenzyl)-2-(methylsulfanyl)-1H-benzimidazole resulted in substitution of the methoxy group by methylamino.
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About the authors
A. A. Harutyunyan
Mndzhoyan Institute of Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry
Author for correspondence.
Email: harutyunyan.arthur@yahoo.com
Armenia, pr. Azatutyan 26, Yerevan, 0014
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