Phase Transformations in Self-Organized System Based on Lecithin

Abstract

Phase diagram was obtained for the first time and processes of lecithin self-organization in the water/ propylene glycol/lecithin/Vaseline oil system were examined. Tensiometric data were used to find the optimal composition of the components, necessary for providing the stability of this system. Specific features of the microemulsion–liquid crystal structural-phase transition were examined. It was shown that both the packing type of molecules and the type of distribution of dispersed-phase particles change in this transition. The systems under study are promising for delivery of medicinal and biologically active substances into cells.