Dynamics of Uric Acid Sorption on Molecularly Imprinted Sorbent


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Abstract

In order to create an effective sorption method for extracting uric acid from blood plasma, the dynamics of uric acid sorption by a granular molecular imprinted polymer sorbent based on 2-hydroxyethyl methacrylate and ethylene glycol dimethacrylate and its non-imprinted analog were investigated. The speed intervals of the mobile phase were determined, in which the equilibrium mode of the dynamics of sorption of uric acid on the molecularly imprinted sorbent MIS-40 is realized. The optimal mode of the dynamic sorption process on MIS-40 was determined, at which the degree of extraction of uric acid from saline solution was 60% and the selectivity coefficient was 2.08.

About the authors

I. S. Garkushina

Institute of Macromolecular Compounds

Author for correspondence.
Email: chrom79@yandex.ru
Russian Federation, St. Petersburg, 199004

I. V. Polyakova

Institute of Macromolecular Compounds

Email: chrom79@yandex.ru
Russian Federation, St. Petersburg, 199004

O. A. Pisarev

Institute of Macromolecular Compounds; Peter the Great Polytechnic University

Email: chrom79@yandex.ru
Russian Federation, St. Petersburg, 199004; St. Petersburg, 195251

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