Synthesis and Pharmacological Activity of Tris(2-hydroxyethyl)ammonium 4-Chlorophenylsulfonylacetate


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详细

Methods for the synthesis of 4-chlorophenylsulfonylacetic acid and its tris(2-hydroxyethyl)ammonium salt (“sulfacetamine”) were studied. The results of in vitro and in vivo experiments showed that sulfacetamine possesses high antithrombotic, antioxidant, hypocholesterolemic, immunostimulating, and protective-adaptive activities.

作者简介

S. Adamovich

Favorsky State Institute of Chemistry, Siberian Branch; Irkutsk Scientific Center, Siberian Branch

Email: mir@irioch.irk.ru
俄罗斯联邦, ul. Favorskogo 1a, Irkutsk, 664033; ul. Lermontova 134, Irkutsk, 664033

E. Oborina

Favorsky State Institute of Chemistry, Siberian Branch; Irkutsk Scientific Center, Siberian Branch

Email: mir@irioch.irk.ru
俄罗斯联邦, ul. Favorskogo 1a, Irkutsk, 664033; ul. Lermontova 134, Irkutsk, 664033

A. Mirskova

Favorsky State Institute of Chemistry, Siberian Branch

编辑信件的主要联系方式.
Email: mir@irioch.irk.ru
俄罗斯联邦, ul. Favorskogo 1a, Irkutsk, 664033

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