Email this article Synthesis and Pharmacological Activity of Tris(2-hydroxyethyl)ammonium 4-Chlorophenylsulfonylacetate
- Authors: Adamovich S.N.1,2, Oborina E.N.1,2, Mirskova A.N.1
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Affiliations:
- Favorsky State Institute of Chemistry, Siberian Branch
- Irkutsk Scientific Center, Siberian Branch
- Issue: Vol 91, No 4 (2018)
- Pages: 701-705
- Section: Brief Communications
- URL: https://journals.rcsi.science/1070-4272/article/view/215811
- DOI: https://doi.org/10.1134/S1070427218040249
- ID: 215811
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Abstract
Methods for the synthesis of 4-chlorophenylsulfonylacetic acid and its tris(2-hydroxyethyl)ammonium salt (“sulfacetamine”) were studied. The results of in vitro and in vivo experiments showed that sulfacetamine possesses high antithrombotic, antioxidant, hypocholesterolemic, immunostimulating, and protective-adaptive activities.
About the authors
S. N. Adamovich
Favorsky State Institute of Chemistry, Siberian Branch; Irkutsk Scientific Center, Siberian Branch
Email: mir@irioch.irk.ru
Russian Federation, ul. Favorskogo 1a, Irkutsk, 664033; ul. Lermontova 134, Irkutsk, 664033
E. N. Oborina
Favorsky State Institute of Chemistry, Siberian Branch; Irkutsk Scientific Center, Siberian Branch
Email: mir@irioch.irk.ru
Russian Federation, ul. Favorskogo 1a, Irkutsk, 664033; ul. Lermontova 134, Irkutsk, 664033
A. N. Mirskova
Favorsky State Institute of Chemistry, Siberian Branch
Author for correspondence.
Email: mir@irioch.irk.ru
Russian Federation, ul. Favorskogo 1a, Irkutsk, 664033
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