Microparticles based on chitosan–hyaluronic acid interpolyelectrolyte complex, which provide stability of aqueous dispersions

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Abstract

Turbidimetric titration and laser scattering methods were used to assess the phase behavior of mixtures of chitosan and hyaluronic acid in aqueous solutions in relation to interaction conditions. Conditions were found in which stable water dispersions with particle size of up to 573 nm can be obtained. It was found that the molar ratios and the overall concentration mode of the starting-polyelectrolyte solutions affect the particle size.

About the authors

M. S. Gurina

Ufa Institute of Chemistry

Author for correspondence.
Email: Gurina.MS@yandex.ru
Russian Federation, pr. Oktyabrya 71, Ufa, Bashkortostan, 450054

R. R. Vil’danova

Ufa Institute of Chemistry

Email: Gurina.MS@yandex.ru
Russian Federation, pr. Oktyabrya 71, Ufa, Bashkortostan, 450054

L. A. Badykova

Ufa Institute of Chemistry

Email: Gurina.MS@yandex.ru
Russian Federation, pr. Oktyabrya 71, Ufa, Bashkortostan, 450054

N. M. Vlasova

Ufa Institute of Chemistry

Email: Gurina.MS@yandex.ru
Russian Federation, pr. Oktyabrya 71, Ufa, Bashkortostan, 450054

S. V. Kolesov

Ufa Institute of Chemistry

Email: Gurina.MS@yandex.ru
Russian Federation, pr. Oktyabrya 71, Ufa, Bashkortostan, 450054

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